体外受精-胚胎移植中含单绒毛膜双胎的三胎减胎术后妊娠结局分析

发布时间：2018-11-10 23:32

【摘要】：目的:探讨体外受精-胚胎移植(IVF-ET)中移植2枚胚胎后发生三胎妊娠行单绒毛膜双胎中一胎减灭术后的妊娠结局。方法:回顾性分析27例行单绒毛膜双胎中一胎减灭术的三胎妊娠患者的临床资料,了解术后一般情况,并对比术后仍保留双胎妊娠的与同期非减胎双胎妊娠的妊娠结局及新生儿情况。结果:减胎术后有12例(44.44%)发生自然减灭仅留一胎;保留双胎组与非减胎双胎组患者平均年龄、平均孕周及平均胎儿出生体质量无统计学差异(P0.05);早期均无流产发生,晚期流产率分别为6.67%和10.00%,抱婴回家率分别为93.33%、90.00%,早产率分别为21.43%和37.04%,低体质量儿出生比例分别为21.43%和33.33%,围产儿死亡率分别为0.0%和3.7%,组间均无统计学差异(P0.05),减胎后双胎组和非减胎双胎组均无畸形儿出生。结论:行减灭单绒毛膜双胎中一胎的减胎术有近一半的患者另一胎会发生自然减灭,余保留双胎的妊娠结局和新生儿一般情况与非减胎双胎妊娠组无统计学差异。
[Abstract]:Aim: to investigate the pregnancy outcome after in vitro fertilization-embryo transfer (IVF-ET) with two embryos after three pregnancies and one of the single chorionic twins. Methods: the clinical data of 27 pregnant women who underwent single chorionic twin pregnancy were analyzed retrospectively. The pregnancy outcome and neonatal status of twin pregnancy and non-decreasing twin pregnancy after operation were compared. Results: there were 12 cases (44.44%) with natural reduction and only one fetus occurred after fetal reduction, and there was no significant difference in mean age, mean gestational week and mean birth weight between the twin group and the non-decreasing twin group (P0.05). There was no miscarriage in the early stage, the late abortion rate was 6.67% and 10.00%, the rate of home delivery was 93.33 and 90.005, the premature delivery rate was 21.43% and 37.04%, respectively. The birth rates of low birth weight infants were 21.43% and 33.33%, perinatal mortality rates were 0.0% and 3.7%, respectively. There was no significant difference between the two groups (P0.05). Conclusion: nearly half of the patients with single chorionic twins who underwent the operation of reducing the number of chorionic twins and the other one had the spontaneous elimination. There was no statistical difference between the pregnancy outcome of the remaining twins and the general situation of the newborns compared with that of the non-reduced twins group.
【作者单位】：河南省人民医院生殖中心;
【分类号】：R714.8

【共引文献】