复方苦参注射液及顺铂联合微波热疗治疗卵巢癌腹水的临床观察

发布时间：2018-11-13 17:48

【摘要】：目的:观察腹腔灌注复方苦参注射液及顺铂联合微波热疗治疗卵巢癌腹水患者的疗效及毒副反应。方法:将患者分为2组,研究组39例以915MHz型大功率微波腹部区域热疗联合复方苦参注射液及顺铂腹腔灌注。对照组39例行复方苦参注射液及顺铂腹腔灌注,未行腹部热疗。结果:全部患者均顺利完成治疗,研究组39例中完全缓解(CR)26例,部分缓解(PR)7例,有效(CR+PR)率为84.62%。对照组39例中CR 17例,PR 6例,有效率为58.98%。两组有效率比较,差异有显著性(P0.05)。结论:915MHz型大功率微波腹部区域热疗联合复方苦参注射液及顺铂腹腔灌注治疗卵巢癌腹水,疗效较单纯腹腔灌注复方苦参注射液及顺铂疗效好,未增加毒副反应,提高了治疗效果。
[Abstract]:Objective: to observe the efficacy and side effects of intraperitoneal infusion of compound Sophora flavescens injection and cisplatin combined with microwave hyperthermia in patients with ovarian cancer ascites. Methods: the patients were divided into two groups. 39 patients in the study group were perfused intraperitoneally with 915MHz type high power microwave hyperthermia combined with compound Sophora flavescens injection and cisplatin. The control group (39 cases) received compound Sophora flavescens injection and cisplatin intraperitoneal perfusion without abdominal hyperthermia. Results: all the patients completed the treatment successfully. In the study group, 26 cases had complete remission of (CR) and 7 cases had partial remission of (PR). The effective (CR PR) rate was 84.62%. In the control group, 17 cases were CR and 6 cases were PR, the effective rate was 58.98%. There was a significant difference in the effective rate between the two groups (P0.05). Conclusion: the efficacy of 915MHz type microwave hyperthermia combined with compound Sophora flavescens injection and cisplatin intraperitoneal infusion in the treatment of ovarian cancer ascites is better than that of simple abdominal perfusion of compound Sophora flavescens injection and cisplatin injection. The therapeutic effect was improved.
【作者单位】：邯郸市肿瘤医院;武安市新兴际华集团有限公司职工医院;
【分类号】：R737.31

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