CZF超声波妇科治疗仪与微波仪比较治疗慢性宫颈炎有效性和安全性Meta分析

发布时间：2018-11-16 21:47

【摘要】：目的:系统评价CZF超声波妇科治疗仪治疗慢性宫颈炎的临床疗效。方法:计算机检索Medline、Embase、Pub Med、中国生物医学文献数据库(CBM)、维普中文科技期刊全文数据库(VIP)、中国知识资源总库(CNKI)、万方数字化期刊全文数据库(WF),查找以CZF超声波妇科治疗仪治疗慢性宫颈炎的随机对照试验(randomized controlled trials,RCTs)或对照试验,对纳入的研究进行质量评价,采用Rev Man5.2软件进行Meta分析。结果:共纳入9项RCTs,共4 336例患者(治疗组2 890例患者,对照组1 446例患者)。Meta分析结果显示,治疗组总有效率较对照组好(RR=1.08,95%CI=1.04~1.13,P=0.000),针对于慢性宫颈炎的具体分型,治疗组治疗轻度慢性宫颈炎的有效率与对照组无明显统计学差异(RR=1.00,95%CI=0.99~1.02,P=0.72),但在治疗中度、重度慢性宫颈炎而言,治疗组有效率则要明显优于对照组(RR=1.07,95%CI=1.01~1.14,P=0.02)和(RR=1.24,95%CI=1.09~1.42,P=0.001)。治疗组治疗后阴道排液、阴道出血、宫颈结痂及瘢痕形成等的发生例数较对照组少,阴道排液(RR=0.25,95%CI=0.11~0.56,P=0.000);阴道出血(RR=0.14,95%CI=0.08~0.25,P=0.000);宫颈结痂(RR=0.01,95%CI=0.00~0.07,P=0.000);宫颈瘢痕形成(RR=0.01,95%CI=0.00~0.02,P=0.000)。结论:CZF超声波妇科治疗仪治疗慢性宫颈炎较微波治疗疗效好,且可以减少治疗后的不良反应及后遗症。
[Abstract]:Objective: to evaluate the clinical effect of CZF ultrasonic gynecological therapy instrument on chronic cervicitis. Methods: Medline,Embase,Pub Med, Chinese biomedical literature database (CBM), Weipu full text database of Chinese scientific and technological journals (VIP), Chinese knowledge resource database (CNKI), Wanfang digital full text journal database (WF), A randomized controlled trial (randomized controlled trials,RCTs) or a controlled trial with CZF ultrasonic gynecologic therapeutic instrument for the treatment of chronic cervicitis was found. The quality of the included studies was evaluated and the Meta analysis was carried out with Rev Man5.2 software. Results: a total of 4 336 patients (2 890 cases in the treatment group and 1 446 cases in the control group) were included in 9 items of RCTs,. The results of). Meta analysis showed that the total effective rate of the treatment group was better than that of the control group (RR=1.08,95%CI=1.04~1.13,P=0.000). According to the specific classification of chronic cervicitis, the effective rate of treating mild chronic cervicitis in the treatment group was not significantly different from that in the control group (RR=1.00,95%CI=0.99~1.02,P=0.72), but in the treatment of moderate and severe chronic cervicitis, The effective rate of the treatment group was significantly better than that of the control group (RR=1.07,95%CI=1.01~1.14,P=0.02) and (RR=1.24,95%CI=1.09~1.42,P=0.001). There were fewer cases of vaginal effusion, vaginal bleeding, cervical crusts and scar formation after treatment in the treatment group than in the control group. Vaginal effusion (RR=0.25,95%CI=0.11~0.56,P=0.000), vaginal bleeding (RR=0.14,95%CI=0.08~0.25,P=0.000), and so on were less in the treatment group than in the control group. Cervical scab (RR=0.01,95%CI=0.00~0.07,P=0.000); cervix scar formation (RR=0.01,95%CI=0.00~0.02,P=0.000). Conclusion: CZF ultrasonic gynecologic therapeutic instrument is more effective than microwave in the treatment of chronic cervicitis, and can reduce the adverse reactions and sequelae after treatment.
【作者单位】：重庆医科大学生物医学工程学院省部共建国家重点实验室培育基地—重庆市超声医学工程重点实验室重庆市生物医学工程学重点实验室;中国人民解放军总医院超声科;
【基金】：十二·五科技支撑计划资助项目(编号:2011BAI14B01) 国家科技部973计划资助项目(编号:2011CB707900)
【分类号】：R711.32

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