2140例不孕患者夫精宫腔内人工授精的临床效果及其影响因素
发布时间:2018-11-18 09:20
【摘要】:目的观察2 140例不孕患者夫精宫腔内人工授精(IUI)的临床效果,并分析其影响因素。方法 2 140例不孕患者,均行IUI治疗,共治疗3 383个IUI周期,采用B超测量HCG日患者子宫内膜厚度,计算直径≥14 mm卵泡数。IUI后第30天计算临床妊娠率、抱婴率、流产率、异位妊娠率、多胎妊娠率。分析IUI的临床妊娠率、抱婴率与不孕症患者年龄、不孕类型、不孕原因、IUI次数的关系。结果 3 383个IUI周期中患者HCG日子宫内膜厚度(9.4±2.0)mm,直径≥14 mm卵泡数(2.6±1.9)个。IUI后第30天时临床妊娠率15.0%(508/3 383),抱婴率11.1%(375/3 383)。流产率16.9%(86/508),异位妊娠率8.9%(45/508),其中宫内妊娠合并宫外妊娠者4例、双胎妊娠58例、三胎妊娠8例、四胎妊娠3例,多胎妊娠率13.6%(69/508)。女性年龄40岁者临床妊娠率、抱婴率明显低于其余年龄者,P均0.05。原发不孕与继发不孕患者的临床妊娠率分别为14.8%(285/1 921)、15.3%(223/1 462),抱婴率分别为10.9%(209/1 921)、11.4%(166/1 462),二者比较,P均0.05。39~40岁原发不孕患者抱婴率明显低于继发不孕者,P0.05。女性因素不孕患者临床妊娠率、抱婴率均低于混合因素者,P均0.05。不同IUI周期次数之间临床妊娠率与抱婴率间比较差异无统计学意义。结论 IUI的成功率仍较低,女性年龄40岁、提高IUI周期次数是提高IUI妊娠结局的重要因素,临床中应综合分析女性年龄、不孕类型、不孕原因选择合适助孕方案。
[Abstract]:Objective to observe the clinical effect of intrauterine insemination (IUI) in 2 140 infertile patients and analyze its influencing factors. Methods 2,140 infertile patients were treated with IUI for 3 383 IUI cycles. Endometrial thickness was measured by B-ultrasound on HCG day, and the number of follicles with diameter 鈮,
本文编号:2339619
[Abstract]:Objective to observe the clinical effect of intrauterine insemination (IUI) in 2 140 infertile patients and analyze its influencing factors. Methods 2,140 infertile patients were treated with IUI for 3 383 IUI cycles. Endometrial thickness was measured by B-ultrasound on HCG day, and the number of follicles with diameter 鈮,
本文编号:2339619
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