前置胎盘与小于胎龄儿关系的临床研究

发布时间：2018-11-24 15:33

【摘要】：目的研究前置胎盘及类型是否会影响新生儿体质量,增加小于胎龄儿(SGA)的发生率。方法回顾性分析290例于2013年1月至2016年12月在该院产科住院的前置胎盘患者的临床资料;随机选择同期住院的290例非前置胎盘孕妇为对照组。采用χ~2检验、标准t检验比较分析前置胎盘及其类型对胎儿孕周、新生儿体质量、SAG的影响,并采用Logistic回归分析不同类型前置胎盘与不良妊娠结局的关系。结果与非前置胎盘组相比,前置胎盘组患者年龄偏大[(30.9±4.6)岁vs.(29.1±4.0)岁,P0.01],孕次偏多[(3.2±1.8)次vs.(2.2±1.4)次,P0.01],产次偏多[(1.4±0.7)次vs.(1.1±0.6)次,P0.01],产时孕周偏小[(37.7±1.7)周vs.(39.0±1.5)周,P0.01]。完全性前置胎盘、凶险性前置胎盘新生儿体质量分别为(3 038.1±450.0)、(2 940.9±503.0)g,与非前置胎盘组相比,体质量均明显偏低(P0.05)。经校正孕妇年龄、孕次、产次、妊娠期糖尿病(GDM)、胎龄等风险因素后,完全性前置胎盘、凶险性前置胎盘SGA发生风险稍偏高[(OR1.21,95%CI(0.29,6.02);OR2.25,95%CI(0.88,5.77)],但差异无统计学意义(P0.05)。结论完全性前置胎盘、凶险性前置胎盘SGA的发生风险偏高。
[Abstract]:Objective to study whether placenta previa and type of placenta previa affect the body mass and increase the incidence of (SGA) in infants with small gestational age. Methods the clinical data of 290 pregnant women with placenta previa who were hospitalized in obstetrics department from January 2013 to December 2016 were analyzed retrospectively, and 290 pregnant women without placenta previa were randomly selected as control group. The effects of placenta previa and its type on gestational weeks, neonatal body mass and SAG were analyzed by 蠂 ~ 2 test and standard t test. Logistic regression analysis was used to analyze the relationship between placenta previa of different types and adverse pregnancy outcome. Results the age of placenta previa group was older than that of non-placenta group [(30.9 卤4.6) years old, vs. (29.1 卤4.0) years old, P0.01], and the number of pregnancy times was higher [(3.2 卤1.8) times vs. times, P 0.01], but not in placenta previa group [(30.9 卤4.6) years old, (29.1 卤4.0) years old, P0.01]. The number of vs. was (1.4 卤0.7) times, and the gestational week was small [(37.7 卤1.7) weeks, (39.0 卤1.5) weeks, P 0.01]. The body weight of complete placenta previa and dangerous placenta previa was (3 038.1 卤450.0), (2 940.9 卤503.0) g, which was significantly lower than that of non-placenta group (P0.05). After adjusting the risk factors such as age, pregnancy, delivery, gestational diabetes mellitus (GDM),) gestational age, the risk of complete placenta previa and dangerous placenta previa was slightly higher [OR1.21,95%CI (0.29 卤6.02)]; OR2.25,95%CI (0.88 卤5.77), but the difference was not statistically significant (P0.05). Conclusion there is a high risk of SGA in complete placenta previa and dangerous placenta previa.
【作者单位】：重庆医科大学附属第一医院重症医学科;重庆医科大学附属第一医院产科;
【基金】：国家自然科学基金资助项目(81520108013;81170585;81300509)
【分类号】：R714.2

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