生殖道感染解脲脲支原体与沙眼衣原体对胎膜早破的影响研究

发布时间：2018-12-06 16:35

【摘要】：目的分析生殖道解脲脲支原体(Uu)及沙眼衣原体(Ct)感染对孕妇胎膜早破的影响,为临床早期干预提供依据。方法选取医院2012年1月-2014年6月收治的胎膜早破孕妇72例为观察组,另选同期待产的健康孕妇72例为对照组,采用实时荧光PCR方法对两组孕妇生殖道分泌物进行Uu、Ct感染的检测,分析Uu、Ct感染对孕妇胎膜早破的影响。结果观察组孕妇宫颈分泌物Uu、Ct及Uu+Ct的检出率分别为62.5%、23.6%及12.5%,均较对照组显著升高,差异有统计学意义(P0.05);观察组孕妇中早产孕妇Uu、Ct检出率分别为75.0%、34.3%,均较足月产孕妇Uu、Ct检出率显著提高,差异有统计学意义(P0.05)。结论生殖道感染Uu及Ct对胎膜早破具有一定的影响,易引发胎膜早破孕妇发生早产,影响母婴健康,临床上应重视孕妇的早期筛查,及时采取防治措施。
[Abstract]:Objective to analyze the effect of Ureaplasma Urealyticum (Uu) and Chlamydia trachomatis (Ct) infection on premature rupture of fetal membrane in pregnant women. Methods from January 2012 to June 2014, 72 pregnant women with premature rupture of membranes were selected as observation group and 72 healthy pregnant women as control group. Uu, was performed by real-time fluorescence PCR. Detection of Ct infection and analysis of Uu,Ct infection on premature rupture of membranes in pregnant women. Results the detection rates of Uu,Ct and Uu Ct in cervical secretion of pregnant women in the observation group were 62.5% and 12.5% respectively, which were significantly higher than those in the control group (P0.05). The detection rate of Uu,Ct in the observation group was 75. 0% and 34. 3% respectively, which was significantly higher than that in the term delivery group (P0.05). Conclusion Uu and Ct infection of reproductive tract infection have certain influence on premature rupture of membranes, which can easily lead to premature delivery of pregnant women with premature rupture of membranes and affect the health of mother and child. Early screening of pregnant women should be paid attention to in clinical practice and preventive measures should be taken in time.
【作者单位】：浙江省平阳县人民医院妇产科;温州市人民医院妇产科;杭州师范大学医学院临床医学系;
【基金】：浙江省医药卫生科技计划基金资助项目(2012YCG107)
【分类号】：R714.433

【参考文献】