国际糖尿病妊娠研究组新诊断标准调查妊娠期糖尿病患病率及其危险因素分析

发布时间：2018-12-09 19:48

【摘要】：目的观察国际糖尿病妊娠研究组(IADPSG)新的诊断标准调查GDM的患病情况,并分析危险因素。方法采用调查问卷方法收集患者的一般资料,于24~28周行75g OGTT,测定0h、1h、2hPG,并检测TC、TG等指标。采用Pearson相关分析和Logistic回归分析GDM的危险因素。结果最终完成者690例,GDM患病率为33.3%(230/690)。GDM组年龄、孕前体重、孕前BMI、孕期体重增加(孕前体重-初次建卡时体重)、新生儿体重、TG均高于NGT组(P0.05)。随年龄、孕前BMI增加,GDM患病率增加,35岁者的患病率是25岁者的2.06倍。BMI28kg/m2者GDM患病率达71.43%(10/14)。GDM组多次妊娠和既往不良妊娠比例增高。Logistic回归分析显示,糖尿病家族史、剖宫产史、巨大儿生育史是GDM独立危险因素。结论新诊断标准使GDM患病率增加,宜针对GDM的危险因素实施防治,以降低GDM发病率。
[Abstract]:Objective to investigate the prevalence and risk factors of (IADPSG) in the International Diabetic pregnancy study Group. Methods the general data of the patients were collected by questionnaire, and 75 g OGTT, was used to determine 0hU 1h hPGand 2 hPGs at 24 ~ 28 weeks, and TC,TG and other indexes were detected. Pearson correlation analysis and Logistic regression analysis were used to analyze the risk factors of GDM. Results the prevalence of GDM was 33. 3% (230 / 690). GDM age, weight before pregnancy, weight gain during pregnancy (pre-pregnancy weight-first time weight), weight of newborns), before pregnancy (pre-gestational weight-weight at first establishment of card), the prevalence of GDM was 33. 3% (age of 230 / 690). GDM group). TG was higher than NGT group (P0.05). With age, BMI increased before pregnancy, and the prevalence of GDM increased. The prevalence of GDM in BMI28kg/m2 patients was 71.43% (10 / 14). GDM group), and the proportion of multiple pregnancies and previous adverse pregnancies was increased. Logistic regression analysis showed that the family history of diabetes mellitus and cesarean section history, The history of macrosomia is an independent risk factor for GDM. Conclusion the new diagnostic criteria increase the prevalence of GDM. It is appropriate to prevent and cure the risk factors of GDM in order to reduce the incidence of GDM.
【作者单位】：河南科技大学第一附属医院内分泌科;
【基金】：洛阳市科技攻关计划(1301070A-3)
【分类号】：R714.256

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