多囊卵巢综合征患者相关危险因素的调查与研究

发布时间：2018-12-14 06:35

【摘要】：目的探讨多囊卵巢综合征患者相关危险因素,为预防多囊卵巢综合征的发生以及多囊卵巢综合征患者调整生活方式、提高治疗效果提供科学依据。方法本研究采用病例对照研究方法,应用自制的多囊卵巢综合征调查表,包括一般资料、生活习惯、临床特征,对138例多囊卵巢综合征患者和152例健康女性进行调查。使用SPSS 20.0统计软件对数据进行分析:比较病例组和对照组中各因素间的差异,采用卡方检验;对单因素分析显示有统计学意义的变量进行非条件Logistic回归分析,筛查多囊卵巢综合征的危险因素。结果1、单因素分析显示:文化程度、医疗费用支付方式、暴饮暴食、食用减肥药、饮酒、吸烟、运动习惯、睡眠质量、焦虑、家族母系月经紊乱史、家族父系早秃史、家族肥胖史、家族糖尿病史、生育情况、不孕情况、月经周期、月经经期、月经经量、体质指数、多毛、痤疮可能是多囊卵巢综合征发病的相关因素(P0.05)。2、非条件Logistic回归分析显示:焦虑(OR=7.399,95%CI:3.044~17.984)、家族肥胖史(OR=8.582,95%CI:1.976~37.280)、吸烟(OR=3.583,95%CI:1.550~8.282)、不孕(OR=7.247,95%CI:2.081~25.240)、月经周期(OR=8.190,95%CI:2.189~30.638)、月经经期(OR=3.772,95%CI:2.036~6.805)、月经经量(OR=4.821,95%CI:1.300~17.874)、体质指数(OR=22.054,95%CI:6.057~80.302)、多毛(OR=2.042,95%CI:1.097~3.801)可能是多囊卵巢综合征发病的相关危险因素。而月生育情况(OR=0.530,95%CI:0.097~2.097),是多囊卵巢综合征的保护因素。结论1、多囊卵巢综合征发病的相关危险因素为体质指数、家族肥胖史、月经周期、焦虑、不孕、月经经量、月经经期、吸烟、多毛,而生育情况是多囊卵巢综合征的保护因素。2、针对所筛选出的危险因素,社会相关部门应积极开展育龄女性多囊卵巢综合征相关健康教育,尤其是提高多囊卵巢综合征高危人群的防病意识。临床确诊的多囊卵巢综合征患者采取应积极应对措施,减轻或去除危险因素,提高治疗效果。
[Abstract]:Objective to investigate the risk factors of polycystic ovary syndrome (PCOS) and to provide scientific evidence for prevention of PCOS and adjustment of life style in patients with PCOS. Methods A case-control study was conducted to investigate 138 patients with polycystic ovary syndrome (PCOS) and 152 healthy women with polycystic ovary syndrome (PCOS) questionnaire, including general information, living habits and clinical characteristics. SPSS 20.0 statistical software was used to analyze the data. The differences between the factors in the case group and the control group were compared and chi-square test was used. Non-conditional Logistic regression analysis was used to screen the risk factors of polycystic ovary syndrome (PCOS). Results 1. Univariate analysis showed that: education, medical expenses, overeating, diet, alcohol consumption, smoking, exercise habits, sleep quality, anxiety, family history of maternal menstrual disorder, family history of early baldness; Family history of obesity, family history of diabetes, fertility, infertility, menstrual cycle, menstrual volume, body mass index, hirsutism, acne may be the related factors of polycystic ovary syndrome (P0.05). Non-conditional Logistic regression analysis showed that anxiety (OR=7.399,95%CI:3.044~17.984), family history of obesity (OR=8.582,95%CI:1.976~37.280), smoking (OR=3.583,95%CI:1.550~8.282), Infertility (OR=7.247,95%CI:2.081~25.240), menstrual cycle (OR=8.190,95%CI:2.189~30.638), menstrual cycle (OR=3.772,95%CI:2.036~6.805), menstrual volume (OR=4.821,95%CI:1.300~17.874), Body mass index (OR=22.054,95%CI:6.057~80.302) and polyhair (OR=2.042,95%CI:1.097~3.801) may be the risk factors of polycystic ovary syndrome (PCOS). Monthly fertility (OR=0.530,95%CI:0.097~2.097) is a protective factor for polycystic ovary syndrome (PCOS). Conclusions 1. The risk factors of polycystic ovary syndrome are body mass index, family history of obesity, menstrual cycle, anxiety, infertility, menstrual volume, menstrual period, smoking, hairy. Fertility is the protective factor of polycystic ovary syndrome. 2. In view of the risk factors screened out, social departments should actively carry out health education related to polycystic ovary syndrome among women of childbearing age. In particular, to improve the high-risk population of polycystic ovary syndrome awareness of disease prevention. The patients with polycystic ovary syndrome (PCOS) should take active measures to reduce or remove risk factors and improve the therapeutic effect.
【学位授予单位】：锦州医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R711.75

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