绝经前女性子宫内膜癌123例临床分析

发布时间：2019-01-30 13:10

【摘要】：目的：探讨绝经前女性子宫内膜癌的发病高危因素、临床表现及漏误诊情况。方法：回顾性分析我院2011年10月至2013年10月间收治的经组织病理学确诊的123例绝经前子宫内膜癌及癌前病变患者的临床资料，分析绝经前患者的临床诊断及漏误诊情况，，并以同期收治的155例绝经后患者为对照，对比分析两组患者的发病相关因素及临床症状。结果：高血压、糖尿病、恶性肿瘤史在绝经后子宫内膜癌患者的发病中有更为重要的影响，而PCOS、雌激素使用史、恶性肿瘤家族史、未生育等与绝经前子宫内膜癌关系更加密切。绝经后子宫内膜癌患者以不规则阴道流血，阴道排液为主要表现，临床表现典型，术前误诊率为2.58%；而绝经前患者以不规则阴道流血，经量增多和（或）经期延长为主要表现，临床表现不典型，漏误诊率高达13.82%。结论：绝经前女性子宫内膜癌的发病高危因素不同于绝经后女性，且临床表现不典型，漏误诊率高，临床上应予以重视，以便于早诊断，早治疗，改善患者预后。
[Abstract]:Objective: to investigate the risk factors, clinical manifestations and misdiagnosis of endometrial carcinoma in premenopausal women. Methods: the clinical data of 123 cases of premenopausal endometrial carcinoma and precancerous lesions diagnosed by histopathology from October 2011 to October 2013 were analyzed retrospectively. The clinical diagnosis and misdiagnosis of premenopausal women were analyzed. With 155 postmenopausal patients as control group, the related factors and clinical symptoms of the two groups were analyzed. Results: the history of hypertension, diabetes and malignant tumor was more important in the pathogenesis of postmenopausal endometrial carcinoma, while the history of estrogen use of PCOS, family history of malignant tumor, Infertility is more closely associated with premenopausal endometrial carcinoma. The main manifestations of postmenopausal endometrial carcinoma were irregular vaginal bleeding and vaginal effusion. The clinical manifestations were typical and the misdiagnosis rate was 2.58. The main manifestations of premenopausal patients were irregular vaginal bleeding with increased menstrual volume and / or prolonged menstrual period. The clinical manifestations were atypical and the misdiagnosis rate of leakage was as high as 13.82%. Conclusion: the high risk factors of endometrial carcinoma in premenopausal women are different from those in postmenopausal women, and the clinical manifestations are atypical and the rate of missed misdiagnosis is high. Therefore, attention should be paid to it in clinical practice so as to facilitate early diagnosis, early treatment and improve the prognosis of the patients.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.33

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