妊娠期高血压综合征严重程度与血小板降低及子宫动脉血流异常的关系

发布时间：2019-03-01 18:02

【摘要】：目的分析妊娠期高血压综合征(妊高征)严重程度与血小板降低及子宫动脉异常症状的关系。方法选取妊高征重度患者(重度组)、轻度患者(轻度组)和正常妊娠者(对照组)各80例。比较三组血小板参数[血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)]、子宫动脉多普勒参数[脐动脉收缩压与舒张压比值(S/D)、阻力指数、搏动指数],分析血小板与子宫动脉血流异常的关系。结果轻度组和重度组PLT均显著低于对照组,MPV、PDW均显著高于对照组(P均0.05);轻度组与重度组S/D、阻力指数和搏动指数均高于对照组(P均0.05);重度组PLT与子宫动脉S/D呈反比(r=-0.78,P0.05),轻度组PLT与子宫动脉S/D呈正比(r=0.80,P0.05)。结论妊高征患者的血小板降低与子宫动脉血流异常均可以反映妊高征的病情程度,在临床诊断中具有一定的价值。
[Abstract]:Objective to analyze the relationship between the severity of pregnancy-induced hypertension syndrome (PIH) and thrombocytopenia and uterine artery abnormalities. Methods 80 patients with PIH (severe group), 80 patients with mild pregnancy (mild group) and 80 patients with normal pregnancy (control group) were selected. The platelet parameters (platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW) uterine artery Doppler parameters (umbilical artery systolic to diastolic pressure ratio) and resistance index were compared among the three groups. Pulsatile index, to analyze the relationship between platelet and uterine artery blood flow abnormality. Results PLT in mild group and severe group was significantly lower than that in control group, MPV,PDW was significantly higher than that in control group (P0.05), resistance index and pulsatility index in mild group and severe group were higher than those in control group (P0.05). In the severe group, the PLT was inversely proportional to the uterine artery (r = 0.78, P 0.05), and the mild group was in direct proportion to the uterine artery SS D (r = 0.80, P 0.05). Conclusion Thrombocytopenia and abnormal uterine artery blood flow in patients with PIH can reflect the severity of PIH and have certain value in clinical diagnosis.
【作者单位】：庆云县人民医院;
【分类号】：R714.246

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