健康体检人群宫颈非典型鳞状细胞检出情况及相关因素分析

发布时间：2019-03-09 16:29

【摘要】：目的了解健康体检人群中女性宫颈非典型鳞状细胞(ASCUS)的检出情况并对其相关因素进行分析。方法选择2011年1月—2013年12月在贵阳医学院附属医院体检中心接受体检的健康妇女29 080例,均进行常规妇科检查、阴道分泌物检查、宫颈脱落细胞检查。分析不同年龄段妇女宫颈ASCUS检出率,不同生殖道感染类型(细菌性阴道病、滴虫性阴道炎、真菌性阴道炎、子宫颈糜烂样改变、宫颈肥大并纳氏囊肿)与宫颈ASCUS检出率的关系及宫颈ASCUS的影响因素。结果宫颈ASCUS 359例,检出率1.23%。不同年龄段妇女宫颈ASCUS检出率比较,差异有统计学意义(P0.05)。20~29岁与50~59岁年龄段比较,差异有统计学意义(χ2=7.772,P=0.005);30~39岁与40~49岁年龄段比较,差异有统计学意义(χ2=8.596,P=0.003);30~39岁与50~59岁年龄段比较,差异有统计学意义(χ2=24.014,P0.001);40~49岁与50~59岁年龄段比较,差异有统计学意义(χ2=5.200,P=0.023);50~59岁与60~84岁年龄段比较,差异有统计学意义(χ2=4.053,P=0.044)。滴虫性阴道炎者宫颈ASCUS检出率高于无滴虫性阴道炎者,子宫颈糜烂样改变者宫颈ASCUS检出率高于无子宫颈糜烂样改变者,宫颈肥大并纳氏囊肿者宫颈ASCUS检出率高于无宫颈肥大并纳氏囊肿者(P0.05)。细菌性阴道病、真菌性阴道炎者宫颈ASCUS检出率与无细菌性阴道病、真菌性阴道炎者比较,差异无统计学意义(P0.05)。Logistic回归分析显示,滴虫性阴道炎、子宫颈糜烂样改变、宫颈肥大并纳氏囊肿与宫颈ASCUS的发生有回归关系(P0.05)。结论不同年龄段ASCUS检出率不同,滴虫性阴道炎、宫颈糜烂样改变、宫颈肥大并纳氏囊肿是引起宫颈ASCUS的高危因素,因此定期宫颈细胞学检查、及时治疗滴虫性阴道炎及宫颈病变是预防宫颈癌的重要途径。
[Abstract]:Objective to investigate the detection of atypical cervical squamous cell (ASCUS) in healthy people and analyze its related factors. Methods from January 2011 to December 2013, 29 080 healthy women underwent routine gynecological examination, vaginal secretion examination and cervical exfoliation cell examination in the physical examination center of Guiyang Medical College affiliated Hospital. The detection rate of cervical ASCUS in women of different ages and the changes of different types of reproductive tract infections (bacterial vaginitis, trichomonal vaginitis, fungal vaginitis, cervical chyme-like change) were analyzed. The relationship between cervical hypertrophy and the detection rate of cervical ASCUS and the influencing factors of cervical ASCUS. Results there were 359 cases of cervical ASCUS, the positive rate was 1.23%. There was a significant difference in the detection rate of cervical ASCUS among women of different ages (P0.05), and there was a significant difference between 20 and 59 years old (蠂 ~ 2, 7.772, P < 0.005), and there was a significant difference between 20 and 59 years old (蠂 ~ 2 = 7.772, P < 0.05). There was a significant difference between the age groups of 30 / 39 and 40 / 49 (蠂 ~ 2 = 8.596, P = 0.003), and between the age groups of 30 / 39 and 50 / 59 (蠂 ~ 2 / 24.014, P < 0.001), and there was a significant difference between the age groups of 30 / 39 and 50 / 59 (蠂 ~ 2 = 8.596, P < 0.001). There was a significant difference between the age groups of 40-49 years and 50-59 years (蠂 ~ 2-5.200, P < 0.023) and between 50-59-year-old and 60-84-year-old (蠂 ~ 2-4. 053, P < 0. 044). The detection rate of cervical ASCUS in patients with trichomonal vaginitis was higher than that in patients without trichomonal vaginitis, and the detection rate of cervical ASCUS in patients with cervical chymoidosis was higher than that in patients without cervical chymoidosis. The detection rate of cervical ASCUS was higher in patients with cervical hypertrophy complicated with Nessler's cyst than in those without cervical hypertrophy and Nessler's cyst (P0.05). There was no significant difference in the detection rate of cervical ASCUS between bacterial vaginosis, fungal vaginitis and non-bacterial vaginosis and fungal vaginitis (P0.05). Logistic regression analysis showed that trichomonas vaginitis and cervical chyme-like changes were found. There was a regression relationship between cervical hypertrophic cyst and cervical ASCUS (P0.05). Conclusion the detection rate of ASCUS in different age groups is different. Trichomonitis vaginitis, cervical erosion-like changes, cervical hypertrophy and Nessler's cyst are the high risk factors of cervical ASCUS. Timely treatment of trichomonal vaginitis and cervical lesions is an important way to prevent cervical cancer.
【作者单位】：贵阳医学院附属医院体检中心;
【基金】：贵州省科学技术基金项目(筑科合2006-2070号) 贵阳市科技局社会发展与民生科技计划(筑科合2012103-25号)
【分类号】：R737.33

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