康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用

发布时间：2019-03-16 16:31

【摘要】：目的探讨康妇炎胶囊在治疗输卵管通而不畅性不孕中的临床应用效果。方法 2012年1月至2014年1月在天津医科大学第二医院根据子宫输卵管造影结果选择轻度输卵管通而不畅患者143例(治疗组89例和对照组54例)和重度输卵管通而不畅患者120例(治疗组77例和对照组43例)。轻度输卵管通而不畅治疗组采用输卵管通液术联合康妇炎胶囊口服,对照组仅行输卵管通液术。重度输卵管通而不畅治疗组采用宫腹腔镜再通手术联合康妇炎胶囊口服,对照组仅行宫腹腔镜再通手术。记录患者12个月内妊娠的情况并计算宫内妊娠率和异位妊娠率等指标。结果轻度输卵管通而不畅治疗组宫内妊娠率显著高于对照组(70.8%对51.9%),差异有统计学意义(P0.05);输卵管妊娠率显著低于对照组(1.1%对7.4%),差异有统计学意义(P0.05);生化妊娠率两组比较(4.5%对7.4%),差异无统计学意义(P0.05)。重度输卵管通而不畅患者治疗组宫内妊娠率显著高于对照组(37.7%对20.9%),差异有统计学意义(P0.05);输卵管妊娠率显著低于对照组(5.2%对16.3%),差异有统计学意义(P0.05);生化妊娠率两组比较(6.5%对9.3%),差异无统计学意义(P0.05)。12个月后轻度输卵管通而不畅治疗组未妊娠患者的输卵管通而不畅率(26.2%对50%)和阻塞率(4.8%对22.2%)均低于对照组,差异有统计学意义(均P0.05);重度输卵管通而不畅治疗组未妊娠患者的输卵管通而不畅率(32.1%对52.2%)和阻塞率(7.7%对21.7%)均低于对照组,差异有统计学意义(均P0.05)。结论康妇炎胶囊在辅助治疗输卵管通而不畅性不孕中具有良好的疗效,可以提高输卵管通而不畅性不孕患者的宫内妊娠率和再通率,同时降低输卵管妊娠率。
[Abstract]:Objective to investigate the clinical effect of Kangfuyan capsule in the treatment of tubal infertility. Methods from January 2012 to January 2014, 143 patients (89 in the treatment group and 54 in the control group) with mild tubal obstruction and severe tubal patency were selected from the second Hospital of Tianjin Medical University according to the results of hysterosalpingography. 120 cases of unobstructed patients (treatment group 77 cases and control group 43 cases). The treatment group was treated with tubal patency combined with Kangfuyan capsule, and the control group was only treated with salpingostomy. The severe tubal patency and obstruction group were treated by uterine laparoscopic recanalization combined with Kangfuyan capsule oral administration, while the control group were only treated with uterine laparoscopic recanalization operation. The pregnancy within 12 months was recorded and the intrauterine pregnancy rate and ectopic pregnancy rate were calculated. Results the intrauterine pregnancy rate in the mild tubal obstruction group was significantly higher than that in the control group (70.8% vs 51.9%), the difference was statistically significant (P0.05). The pregnancy rate of fallopian tube was significantly lower than that of control group (1.1% vs 7.4%) (P0.05), and the biochemical pregnancy rate was 4.5% vs 7.4%, there was no significant difference between the two groups (P0.05). The pregnancy rate in the treatment group was significantly higher than that in the control group (37.7% vs 20.9%), the difference was statistically significant (P0.05). The rate of tubal pregnancy was significantly lower than that of the control group (5.2% vs 16.3%), the difference was statistically significant (P0.05). Biochemical pregnancy rates (6.5% vs 9.3%) were compared between the two groups. 12 months later, the rate of tubal patency and obstruction (26.2% vs 50%) and blocking rate (4.8% vs 22.2%) in the treatment group without tubal obstruction were lower than those in the control group. The difference was statistically significant (all P0.05); The rate of tubal patency and obstruction (32.1% vs 52.2%) and blocking rate (7.7% vs 21.7%) in the severe tubal patency and obstruction group were significantly lower than those in the control group (P 0.05). Conclusion Kangfuyan capsule has a good curative effect in the auxiliary treatment of tubal unsmooth infertility. It can improve the rate of intrauterine pregnancy and recanalization in patients with tubal unsmooth infertility, and reduce the rate of tubal pregnancy at the same time.
【作者单位】：天津医科大学第二医院计划生育科;天津医科大学第二医院放射科;
【分类号】：R711.6

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