妊娠合并甲状腺功能异常分析
发布时间：2019-03-27 15:34
【摘要】：目的建立平湖地区正常妊娠妇女不同孕期甲状腺功能参考值范围,并分析调查本地区妊娠合并甲状腺疾病患病情况。方法对2013年1月-12月在平湖市第二人民医院和平湖市妇幼保健院进行妊娠常规检查的986例妊娠者和150例同期健康体检的非妊娠妇女进行研究,其中786例排除甲状腺疾病高危因素的初产妇作为"标准人群"建立正常参考值范围。采用化学发光免疫法检测TSH、T3、T4、FT3、FT4、TPOAb、TGAb,根据建立的妊娠期特异的甲状腺相关激素参考值范围筛查分析平湖地区妊娠妇女甲状腺疾病患病情况。结果检测的986例孕妇中,甲状腺功能异常(包括甲状腺功能亢进症35例、甲状腺功能减退症1例、亚临床甲状腺功能减退症55例)的总患病率为9.2%(91/986),其中以亚临床甲状腺功能减退症最常见,患病率为5.6%,甲状腺功能亢进症患病率为3.5%。结论平湖地区妊娠妇女合并甲状腺疾病患病率高,甲状腺功能亢进症和亚临床甲状腺功能减退症的患病率明显高于其他地区,建议妊娠早期筛查甲状腺功能。
[Abstract]:Objective to establish the reference range of thyroid function in normal pregnant women during different periods of pregnancy in Pinghu area, and to analyze and investigate the incidence of thyroid diseases during pregnancy in this area. Methods from January to December 2013, 986 pregnant women and 150 non-pregnant women who underwent routine pregnancy examinations were studied in the second people's Hospital of Pinghu City and the Maternal and Child Health Care Hospital of Pinghu City. Among them, 786 primipara who excluded high risk factors of thyroid disease were used as "standard population" to establish a normal reference range. The prevalence of thyroid diseases in pregnant women in Pinghu area was analyzed by chemiluminescence immunoassay (TSH,T3,T4,FT3,FT4,TPOAb,TGAb,) according to the reference range of pregnancy-specific thyroid-related hormones. Results among 986 pregnant women, the total prevalence rate of abnormal thyroid function (including 35 cases of hyperthyroidism, 1 case of hypothyroidism and 55 cases of subclinical hypothyroidism) was 9.2% (91 / 986). Among them, subclinical hypothyroidism is the most common, the prevalence rate is 5.6%, and the prevalence rate of hyperthyroidism is 3.5%. Conclusion the prevalence of thyroid diseases in pregnant women in Pinghu area is high, and the prevalence of hyperthyroidism and subclinical hypothyroidism is significantly higher than that in other areas. It is suggested that early pregnancy should be screened for thyroid function.
【作者单位】： 平湖市第二人民医院;平湖市妇保所;
【基金】：平湖市科技发展计划重点项目(2013-35号)
【分类号】：R714.256
，
本文编号：2448312
[Abstract]:Objective to establish the reference range of thyroid function in normal pregnant women during different periods of pregnancy in Pinghu area, and to analyze and investigate the incidence of thyroid diseases during pregnancy in this area. Methods from January to December 2013, 986 pregnant women and 150 non-pregnant women who underwent routine pregnancy examinations were studied in the second people's Hospital of Pinghu City and the Maternal and Child Health Care Hospital of Pinghu City. Among them, 786 primipara who excluded high risk factors of thyroid disease were used as "standard population" to establish a normal reference range. The prevalence of thyroid diseases in pregnant women in Pinghu area was analyzed by chemiluminescence immunoassay (TSH,T3,T4,FT3,FT4,TPOAb,TGAb,) according to the reference range of pregnancy-specific thyroid-related hormones. Results among 986 pregnant women, the total prevalence rate of abnormal thyroid function (including 35 cases of hyperthyroidism, 1 case of hypothyroidism and 55 cases of subclinical hypothyroidism) was 9.2% (91 / 986). Among them, subclinical hypothyroidism is the most common, the prevalence rate is 5.6%, and the prevalence rate of hyperthyroidism is 3.5%. Conclusion the prevalence of thyroid diseases in pregnant women in Pinghu area is high, and the prevalence of hyperthyroidism and subclinical hypothyroidism is significantly higher than that in other areas. It is suggested that early pregnancy should be screened for thyroid function.
【作者单位】： 平湖市第二人民医院;平湖市妇保所;
【基金】：平湖市科技发展计划重点项目(2013-35号)
【分类号】：R714.256
，
本文编号：2448312
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