不孕与宫颈人乳头瘤病毒感染的关系研究

发布时间：2019-05-10 11:54

【摘要】：目的:调查不孕患者宫颈人乳头瘤病毒(HPV)的感染率及亚型分布。方法:采用快速导流杂交法对217例输卵管不孕患者和174例非输卵管不孕患者进行21种HPV亚型检测。结果:391例不孕患者的HPV阳性率为17.90%,其中输卵管不孕患者的HPV阳性率为20.28%,非输卵管不孕患者的HPV阳性率为14.94%,两组差异无统计学意义(χ2=1.869,P0.05)。HPV阳性的不孕患者中HPV高危型占82.86%,高危型中检出率最高的是HPV 58,其次是HPV 52。输卵管不孕组和非输卵管不孕组HPV感染均以高危型为主,两组间HPV高危型感染率差异无统计学意义(χ2=1.343,P0.05)。结论:HPV高危型感染可能是女性不孕症的危险因素之一,且HPV阳性不孕患者中绝大部分为HPV高危型。
[Abstract]:Objective: to investigate the infection rate and subtype distribution of human papillomavirus (HPV) in infertile women. Methods: 21 subtypes of HPV were detected in 217 patients with tubal sterility and 174 patients with non-tubal sterility. Results: the positive rate of HPV in 391 infertile patients was 17.90%. The positive rate of HPV was 20.28% in oviduct infertility patients and 14.94% in non-tubal infertility patients. There was no significant difference between the two groups (蠂 2 = 1.869, P < 0.01). Among the infertile patients with positive HPV, 82.86% were high risk HPV, the highest was HPV 58, followed by HPV 52. HPV infection in tubal infertile group and non-tubal infertile group was mainly high risk type, but there was no significant difference in HPV high risk infection rate between the two groups (蠂 2 鈮，

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