急性脑梗死感染患者抗氧化能力与血小板参数的变化研究

发布时间：2018-02-23 16:22

本文关键词： 急性脑梗死感染抗氧化能力血小板参数　出处：《中华医院感染学杂志》2016年08期 　论文类型：期刊论文

【摘要】：目的观察急性脑梗死感染患者抗氧化能力及血小板参数的变化,为患者针对性治疗措施的制定提供参考依据。方法选取2010年8月-2015年8月医院收治的52例急性脑梗死发生感染患者为A组,52例急性脑梗死未感染患者为B组,52例感染无急性脑梗死患者为C组,检测3组患者血清抗氧化能力指标及血小板参数,并进行比较,数据采用SPSS 16.0软件进行统计分析。结果 A组患者血小板参数中的MPV、PDW、PLT及PLCR分别为(12.84±1.19)fl、(15.92±1.84)fl、(155.23±14.18)×109/L及(42.90±4.18)%,均差于B组及C组,其血清抗氧化能力指标也均差于B组及C组,B组则均差于C组,且A组与B组中神经功能检查量表(NIHSS)不同评分、A组与C组不同感染严重程度者的检测结果比较,差异均有统计学意义(P0.05)。结论急性脑梗死合并感染患者抗氧化能力及血小板参数的变化较大,且不同脑梗死及感染严重程度者的差异也较为突出,故在干预的过程中应给予充分的重视。
[Abstract]:Objective to observe the changes of antioxidant capacity and platelet parameters in patients with acute cerebral infarction infection. Methods from August 2010 to August 2015, 52 patients with acute cerebral infarction were selected as group A, 52 patients without acute cerebral infarction, 52 patients with acute cerebral infarction, 52 patients with acute cerebral infarction. Group C was infected with no acute cerebral infarction. The serum antioxidant capacity and platelet parameters were measured and compared. The data were statistically analyzed by SPSS 16.0 software. Results the platelet parameters of group A were 12.84 卤1.19, 155.23 卤14.18 脳 10 9 / L and 42.90 卤4.18, respectively, which were different from those of group B and C, respectively. The indexes of serum antioxidant ability were also worse than those of group B and group C, and the results of different scores of NIHSS in group A and group B were compared with those in group A and group C with different infection severity. Conclusion the changes of antioxidant capacity and platelet parameters in patients with acute cerebral infarction complicated with infection were significant, and the differences among patients with different cerebral infarction and severity of infection were also significant. Therefore, in the process of intervention should be given sufficient attention.
【作者单位】：四川省人民医院城东病区内二科;成都军区联勤部机关医院内1科;绵阳市三医院呼吸内科;
【基金】：成都军区联鄞部卫生部软科学基金项目(C12071)
【分类号】：R743.33

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