无创呼吸机辅助救治急性左心衰竭的临床疗效

发布时间：2018-03-13 09:14

本文选题：左心衰竭　切入点：急性　出处：《山东医药》2017年17期 　论文类型：期刊论文

【摘要】：目的探讨无创呼吸机辅助治疗急性左心衰竭的临床疗效。方法选取急性左心衰患者80例,根据治疗方式不同分为观察组和对照组各40例,两组治疗前性别、年龄、临床症状、体征比较差异无统计学意义(P均0.05)。两组均给减轻心脏前后负荷、改善心肌代谢的药物治疗;在此基础上,对照组给予面罩吸氧、观察组给予无创呼吸机正压通气治疗。治疗前、治疗后24 h监测呼吸频率(RR)、心率(HR)、平均动脉压(MBP)、氧分压(PaO_2),检测血清N端-脑钠肽前体(NT-proBNP)、乳酸(LAC),同时比较两组治疗总有效率。结果两组治疗前HR、RR、MBP、PaO_2以及血清NT-proBNP、LAC比较差异无统计学意义(P均0.05)。治疗后24 h,观察组HR、RR、PaO_2、MBP较对照组明显改善(P均0.05),血清NT-proBNP、LAC较对照组明显降低(P均0.05)。观察组总有效率为92.5.00%,对照组总有效率为72.5.00%,两组总有效率比较有统计学差异(P0.05)。结论无创呼吸机正压通气对急性左心衰竭患者有显著疗效。
[Abstract]:Objective to investigate the clinical efficacy of non-invasive ventilator in the treatment of acute left heart failure. Methods 80 patients with acute left heart failure were divided into observation group and control group according to different treatment methods. There was no significant difference in physical signs between the two groups (P < 0.05). The two groups were given drug therapy to reduce the cardiac load and improve myocardial metabolism. On this basis, the control group was given oxygen inhalation by mask, and the observation group was treated with non-invasive ventilator positive pressure ventilation before treatment. 24 hours after treatment, the respiratory frequency, heart rate, mean arterial pressure (MBP) and partial pressure of oxygen (Pao) were monitored. Serum N-terminal brain natriuretic peptide precursor (NT-proBNPN), lactic acid (lactic acid) was detected and the total effective rate of the two groups was compared. Results before treatment, HRRRMBPPaO2 and serum NT-proBNPNP-LAC were lower in both groups. 24 hours after treatment, HRP RPPAO2MBP in the observation group was significantly improved than that in the control group, and serum NT-proBNPLAC was significantly lower than that in the control group. The total effective rate in the observation group was 92.5.00, and the total effective rate in the control group was 72.5.00. The total effective rate in the two groups was higher than that in the control group. The total effective rate in the observation group was 92.5.00 and the total effective rate in the control group was 72.5.00. Conclusion Non-invasive ventilator positive pressure ventilation is effective in patients with acute left heart failure.
【作者单位】：蒙阴县人民医院;山东大学齐鲁医院;
【分类号】：R541.6

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