脉搏指示持续心输出量目标导向液体治疗在重度颅脑损伤患者中的应用

发布时间：2018-03-16 04:15

本文选题：颅脑损伤　切入点：脑灌注　出处：《广东医学》2016年01期 　论文类型：期刊论文

【摘要】：目的探讨脉搏指示持续心输出量(PICCO)目标导向液体治疗在重度颅脑损伤患者麻醉中的应用。方法选取重型颅脑损伤患者168例,随机分为两组,两组患者性别、年龄、体重、ASA分级比较,差异均无统计学意义(P0.05)。A组72例,采用传统液体管理方式;B组96例,应用PICCO进行目标导向液体治疗。观察两组患者手术时间、失血量、输液量和血管活性药物使用量,以及术后并发症情况。结果两组手术时间、失血量比较差异无统计学意义(P0.05);A组输液量、输血量明显多于B组(P0.05),血管活性药物使用量A组少于B组(P0.05),术后并发症发生率A组明显高于B组(P0.05)。结论 PICCO是一种简单、微创的,可对重症患者血液动力学参数进行监测的有效工具,可有效维持机体重要脏器的灌注,减少脑水肿、肺水肿等并发症的发生。
[Abstract]:Objective to investigate the application of targeted fluid therapy with pulse indicator continuous cardiac output (PICCO) in anesthesia of patients with severe craniocerebral injury. Methods 168 patients with severe craniocerebral injury were randomly divided into two groups: sex and age. There were 72 cases in group A and 96 cases in group B with traditional fluid management. The patients were treated with target oriented fluid therapy (PICCO). The operation time and the amount of blood loss were observed in the two groups. Results there was no significant difference in blood loss between the two groups. The volume of blood transfusion was significantly higher than that of group B (P 0.05), the amount of vasoactive drugs used in group A was less than that in group B (P 0.05), and the incidence of postoperative complications in group A was significantly higher than that in group B. conclusion PICCO is simple and minimally invasive. It is an effective tool for monitoring hemodynamic parameters of severe patients and can effectively maintain the perfusion of important organs and reduce the occurrence of complications such as cerebral edema and pulmonary edema.
【作者单位】：沈阳军区总医院麻醉科;
【分类号】：R651.15

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