中重型颅脑损伤中西医结合诊疗方案临床验证疗效分析

发布时间：2018-03-20 00:30

本文选题：颅脑损伤　切入点：中医药疗法　出处：《时珍国医国药》2016年03期 　论文类型：期刊论文

【摘要】：目的根据国家中医药管理局"十一五"重点专科(专病)工作计划和要求,对中西医结合颅脑损伤诊疗方案进行验证,确定其临床疗效和安全性,为进一步优化诊疗方案奠定基础。方法采用非随机、多中心、治疗前后自身对照法,中、重型颅脑损伤患者,接受西医常规治疗,并按诊疗方案进行中医综合治疗。以3周为1个疗程,治疗并观察4个疗程,观察其治疗前后Glasgow(GCS)评分、日常生活活动能力评分、神经功能缺损程度评分及安全指标等,并进行疗效分析及安全性评估。结果颅脑损伤方案能显著改善颅脑损伤患者GCS评分(中型)、神经功能缺损评分及日常生活活动能力评分,总有效率达58.1%,无安全不良事件发生。结论颅脑损伤验证方案能够有效地改善颅脑损伤患者临床症状,是一套疗效可靠、安全的中西医结合综合治疗方案,值得临床推广。
[Abstract]:Objective to confirm the clinical efficacy and safety of integrated Chinese and western medicine in the diagnosis and treatment of craniocerebral injury according to the work plan and requirements of the key specialties (special diseases) in the 11th Five-Year Plan of the State Administration of traditional Chinese Medicine. Methods patients with moderate and severe craniocerebral injury were treated with routine western medicine with non-random, multi-center, self-control method before and after treatment. Three weeks were used as a course of treatment and four courses of treatment were observed. The scores of Glasgowski GCSs, activities of daily living (ADL), neurological impairment and safety indexes were observed before and after treatment. Results the GCS score of patients with craniocerebral injury (medium scale, neurological deficit score and activity of daily living score) was significantly improved by the scheme of craniocerebral injury. Conclusion the verification scheme of craniocerebral injury can effectively improve the clinical symptoms of patients with craniocerebral injury and is a reliable and safe comprehensive treatment scheme of integrated Chinese and western medicine, which is worthy of clinical promotion.
【作者单位】：广西医科大学第一附属医院;中南大学湘雅医院;广西中医药大学附属瑞康医院;
【基金】：广西科技攻关计划(桂科攻1298003-3-4) 广西壮族自治区卫生厅科技项目(No.GZKZ10-106);广西壮族自治区卫生厅自筹经费科研经费课题(No.Z2012116)
【分类号】：R651.15

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