脑外伤所致抑郁障碍的影响因素分析

发布时间：2018-03-23 18:30

本文选题：脑外伤　切入点：抑郁障碍　出处：《安徽医学》2013年05期

【摘要】：目的探讨脑外伤后发生抑郁障碍以及抑郁症状严重程度的相关因素,为阐明其发病机制、筛选高危患者以及建立有效的干预措施提供理论依据。方法以安徽省某医院近3年因急性颅脑损伤住院治疗后出院的患者为研究对象,由2名精神科医师根据DSM-IV诊断标准诊断患者是否患有抑郁症,采用汉密顿抑郁量表(HAMD)评价研究对象抑郁程度,使用自行设计的问卷调查患者的一般情况和临床信息,采用多因素Logistic回归和多元线性回归分析脑外伤后发生抑郁障碍以及抑郁症状严重程度的相关因素。结果多因素Logistic回归结果显示:GCS评分、手术情况、脑干损伤以及残疾与脑外伤所致抑郁障碍有关联(P0.05),GCS评分越高,发生抑郁障碍的风险越低,手术、脑干损伤以及残疾可导致脑外伤后发生抑郁障碍的风险增加。多元线性回归结果显示:GCS评分、手术情况以及残疾与脑外伤患者抑郁症状严重程度有关联(P0.05),GCS评分越高抑郁症状越轻,手术和残疾可导致抑郁症状增加。结论 GCS评分、手术情况、脑干损伤以及残疾是脑外伤后抑郁障碍发生的影响因素,GCS评分、手术情况以及残疾是脑外伤患者抑郁症状严重程度的影响因素。
[Abstract]:Objective to investigate the related factors of depressive disorder and the severity of depressive symptoms after brain injury, and to elucidate its pathogenesis. Methods to select high-risk patients and establish effective intervention measures to provide theoretical basis. Methods A hospital in Anhui Province in recent three years because of acute brain injury patients discharged from hospital as the study object. According to the diagnostic criteria of DSM-IV, two psychiatrists were used to evaluate the depression degree of the subjects, and the general condition and clinical information of the patients were investigated by self-designed questionnaire. Multivariate Logistic regression and multiple linear regression analysis were used to analyze the related factors of depressive disorder and the severity of depressive symptoms after traumatic brain injury. The higher the GCS score of brain stem injury and disability associated with depressive disorder caused by brain trauma, the lower the risk of depressive disorder. Brain stem injury and disability can increase the risk of depressive disorder after brain injury. The degree of depressive symptoms in patients with traumatic brain injury was correlated with the operative condition and the degree of depressive symptoms. Conclusion the higher the score of depression is, the lighter the score of depression is, and the higher the score of depressive symptoms is, the higher the score of depressive symptoms is. Brain stem injury and disability were the influencing factors of depressive disorder after traumatic brain injury and GCS score. The operative condition and disability were the influencing factors of the severity of depressive symptoms in patients with brain trauma.
【作者单位】：安徽医科大学第一附属医院神经外科;望江县人民医院脑外科;
【分类号】：R749.12

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