急诊冠状动脉支架术联合国产替罗非班治疗急性ST段抬高性心肌梗死的临床疗效和安全性

发布时间：2018-04-03 11:25

本文选题：急性ST段抬高性心肌梗死　切入点：急诊　出处：《中国地方病防治杂志》2017年06期

【摘要】：目的探讨急性ST段抬高性心肌梗死患者采取急诊冠状动脉支架术联合国产替罗非班治疗的效果及安全性。方法将我院2013年1月-2016年6月接诊的急性ST段抬高性心肌梗死患者40例作为研究对象,入选对象临床资料完整,愿意配合本研究,随机分组,每组20例。对照组采取急诊冠状动脉支架术治疗,研究组则加用国产替罗非班治疗,对两组患者临床效果、术后并发症发生率、住院时间,以及术后1个月MACE发生率与LVEF进行观察记录,并对比分析。结果研究组患者支架术成功率稍高于对照组,但比较无差异(P0.05);两组患者均有出血、血小板减少发生,研究组发生率显著低于对照组(P0.05);研究组住院时间显著短于对照组(P0.05);研究组术后1个月MACE发生率显著低于对照组,而LVEF则明显高于对照组(P0.05)。结论急诊冠状动脉支架术联合国产替罗非班治疗急性ST段抬高性心肌梗死患者,手术成功率高,而且并发症少,术后不良事件少,能更好地改善心功能,值得借鉴。
[Abstract]:Objective to evaluate the efficacy and safety of emergency coronary stenting combined with tirofiban in patients with acute St segment elevation myocardial infarction.Methods from January 2013 to June 2016, 40 patients with acute ST-segment elevation myocardial infarction (ST-elevation myocardial infarction) received in our hospital from January 2013 to June 2016 were randomly divided into two groups: 20 cases in each group, with complete clinical data and willing to cooperate with this study.The patients in the control group were treated with emergency coronary stenting, and the patients in the study group were treated with domestic tirofiban. The clinical effects, postoperative complications, hospital stay, MACE incidence and LVEF were observed and recorded 1 month after operation.And comparative analysis.Results the success rate of stenting in the study group was slightly higher than that in the control group, but there was no difference between the two groups.The incidence of MACE in the study group was significantly lower than that in the control group (P 0.05), and the hospitalization time in the study group was significantly shorter than that in the control group (P 0.05).Conclusion Emergency coronary stenting combined with domestic tirofiban in the treatment of patients with acute ST-segment elevation myocardial infarction has a high success rate, fewer complications and fewer adverse events, which can improve cardiac function better.
【作者单位】：齐齐哈尔医学院附属第二医院;
【分类号】：R542.22

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