中西医结合治疗方案对急性缺血性脑卒中患者神经功能缺损和致残结局的影响

发布时间：2018-04-03 20:23

本文选题：中西医结合　切入点：康复　出处：《中国中西医结合杂志》2011年09期

【摘要】：目的研究中西医结合治疗方案对急性缺血性脑卒中患者神经功能缺损和近期致残结局的影响。方法 99例患者随机入3组,即:中药灯盏细辛组(A组)、中药苦碟子组(B组)和西医对照组(C组)。A组:灯盏细辛注射液静脉滴注14天,按辨证分型给予中药汤药,并予灯盏生脉胶囊口服2个月;B组:苦碟子注射液静脉滴注14天,按辨证分型给予中药汤药,并予脑栓通胶囊口服2个月;A、B组除接受内科治疗外,还接受针刺、推拿手法、中药外洗治疗21天。C组除接受内科治疗外,还接受现代康复治疗21天,含康复训练及电刺激治疗。采用美国国立卫生研究院卒中量表(NIHSS)和修订致残量表(mRS)作为判断疗效主要指标。结果 3组各时点NIHSS评分均较治疗前明显降低(P0.01),但在各时间点3组间差异均无统计学意义(P0.05)。3组的致残结局随时间后移,经对数线性模型(CATMOD)高维列联表的分析,各组间致残结局差异有统计意义(P0.05)。疗效以B组最优,显效率19.35%,总有效率为54.84%。结论中西医结合治疗方案可改善缺血中风患者的神经功能,而可改善其致残结局,其中以苦碟子静脉滴注加脑栓通胶囊口服加中医辨证施治加针刺、推拿及中药泡洗方案为优。
[Abstract]:Effect of treatment on disability and recent outcomes of nerve function of patients with acute ischemic stroke defect objective to study the combination of traditional Chinese and Western medicine. Methods 99 patients were randomly assigned into 3 groups, namely: Erigeron breviscapus group (A group), Chinese medicine Kudiezi group (B group) and control group (group C).A group: Erigeron breviscapus injection intravenous drip for 14 days, according to syndrome differentiation with traditional Chinese medicine decoction, and to the Dengzhanshengmai capsule orally for 2 months; group B: Kudiezi Injection intravenous drip for 14 days, according to syndrome differentiation with traditional Chinese medicine decoction, and to the Naoshuantong capsule orally for 2 months; A, B group received internal medicine treatment, also received acupuncture, massage, herbal fumigation treatment for 21 days in.C group received medical treatment, also received rehabilitative treatment for 21 days, including rehabilitation training and electrical stimulation treatment. The National Institutes of Health Stroke Scale (NIHSS) and the revised disability scale (mRS) as the main index to judge the curative effect. The results of the 3 groups at each time point NIHSS score was significantly lower than before treatment (P0.01), but the difference between the 3 groups at each time point were not statistically significant (P0.05).3 group disability outcomes over time after the shift, the log linear model (CATMOD) analysis table of high dimensional, disability outcome differences among the groups statistical significance (P0.05). The curative effect in group B optimal, 19.35% significant efficiency, the total effective rate was 54.84%. conclusion combining traditional Chinese and Western medicine treatment can improve the neurological function of patients with ischemic stroke, and can improve the disability outcomes, which Kudiezi intravenous drip plus Naoshuantong capsule orally plus traditional Chinese medicine plus acupuncture. Massage and Chinese medicine bath is the optimal plan.

【作者单位】：广东省中医院;中国中医科学院中医临床基础医学研究所;
【基金】：国家高技术研究发展计划(863)资助课题(No.2007AA02Z4B2)
【分类号】：R743.3

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