疏血通注射液治疗急性脑梗死的临床观察

发布时间：2018-04-12 12:08

本文选题：疏血通注射液 + 急性脑梗死　；参考：《中国药房》2016年03期

【摘要】：目的:观察疏血通注射液治疗急性脑梗死的疗效和安全性。方法:110例急性脑梗死患者随机均分为对照组和观察组。对照组患者给予甘露醇、拜阿司匹林、阿托伐他汀、降糖药物等常规治疗;观察组患者在对照组治疗的基础上给予疏血通注射液6ml加入0.9%氯化钠注射液250 ml中,静脉滴注,每日3次。两组患者疗程均为15 d。观察两组患者的临床疗效,治疗前后美国国立卫生研究院卒中量表(NIHSS)评分和特异性烯醇化酶(NSE)、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子(TNF)-α水平及不良反应发生情况。结果:治疗后,两组患者NIHSS评分和NSE、hs-CRP、TNF-α水平均显著低于同组治疗前,且观察组低于对照组,差异均有统计学意义(P0.05);观察组患者总有效率显著高于对照组,差异有统计学意义(P0.05)。两组患者治疗期间均未见明显不良反应发生。结论:在常规治疗的基础上给予疏血通注射液治疗急性脑梗死的疗效和安全性均较好。
[Abstract]:Objective: To observe the efficacy and safety of Shuxuetong injection in treatment of acute cerebral infarction. Methods: 110 cases of acute cerebral infarction were randomly divided into control group and observation group. The control group were treated with mannitol, aspirin, atorvastatin, conventional treatment of hypoglycemic drugs; the patients in observation group based on the treatment of control group received Shuxuetong injection with 6ml 0.9% Sodium Chloride Injection 250 ml, intravenous drip, 3 times a day. Two patients were treated for 15 D. to observe the clinical curative effect of two groups of patients before and after treatment, the National Institutes of Health Stroke Scale (NIHSS) score and specific enolase (NSE), high sensitive C reactive protein (hs-CRP), tumor necrosis factor (TNF) - alpha levels and incidence of adverse reactions. Results: after treatment, two groups of patients with NIHSS score and NSE, hs-CRP, TNF- levels were significantly lower than the same group before treatment, and the observation group than in the control group, the difference was There was statistical significance (P0.05); the total efficiency of the observation group was significantly higher than the control group, the difference was statistically significant (P0.05). During the two groups of patients had no obvious adverse reactions. Conclusion: on the basis of routine treatment of Shuxuetong injection treatment efficacy and safety of acute cerebral infarction are good.

【作者单位】：佳木斯大学附属第一医院;
【分类号】：R743.33

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