急诊科脓毒症患者罹患因素分析

发布时间：2018-04-16 01:31

本文选题：脓毒症 + 急诊科　；参考：《中国感染与化疗杂志》2016年04期

【摘要】：目的探讨急诊科脓毒症患者的危险因素,为改善预后、降低病死率提供科学依据。方法回顾性分析复旦大学附属华山医院静安分院急诊科病房2011年8月-2014年7月140例脓毒症患者情况。采用单因素分析和多因素Logistic回归分析其危险因素。结果将急诊科3年间出院患者信息数据库中所有数据导入Excel 2007,运用Stata7.0统计软件对660例感染病例(140例脓毒症组和520例非脓毒症组)进行描述性分析和危险因素Logistic回归分析。脓毒症发生率为6.8%,病死率为33.6%。多因素Logistic回归分析发现,甲状腺功能异常和D-二聚体升高是急诊科脓毒症患者发病的独立危险因素。对140例脓毒症组中死亡(67例)与存活(73例)进行多因素Logistic回归分析发现,高龄、血脂异常、甲状腺功能异常和肾功能不全是影响脓毒症预后的危险因素。结论急诊科老年患者居多,脓毒症患病率在逐年增高,脓毒症患者多存在甲状腺功能异常和凝血功能障碍。而高龄、高血脂、血肌酐升高和甲状腺功能异常可作为临床独立预判脓毒症患者不良预后的实验依据。
[Abstract]:Objective to explore the risk factors of sepsis in emergency department and to provide scientific basis for improving prognosis and reducing mortality.Methods 140 patients with sepsis were retrospectively analyzed from August 2011 to July 2014 in the emergency ward of Jing'an Branch Hospital of Huashan Hospital affiliated to Fudan University.Single factor analysis and multivariate Logistic regression analysis were used to analyze the risk factors.Results all the data from the information database of discharged patients in emergency department were imported into Excel 2007. The descriptive analysis and Logistic regression analysis of the risk factors were carried out in 140 sepsis patients and 520 non-sepsis patients with Stata7.0 software.The incidence of sepsis was 6.8 and the mortality was 33.6.Multivariate Logistic regression analysis showed that abnormal thyroid function and increased D-dimer were independent risk factors for sepsis in emergency department.Multivariate Logistic regression analysis showed that elderly age, dyslipidemia, abnormal thyroid function and renal insufficiency were the risk factors affecting prognosis of sepsis.Conclusion the prevalence of sepsis is increasing year by year in the elderly patients in emergency department. The abnormal thyroid function and coagulation dysfunction are often found in sepsis patients.The elderly, hyperlipidemia, elevated serum creatinine and abnormal thyroid function can be used as clinical independent predictors of poor prognosis of sepsis.
【作者单位】：复旦大学附属华山医院急诊科;复旦大学附属华山医院重症医学科;复旦大学附属华山医院静安分院检验科;复旦大学附属华山医院静安分院急诊科;
【分类号】：R459.7

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