延长硬膜下引流时间对促进重型颅脑损伤开颅术后恢复效果的分析

发布时间：2018-04-20 08:58

本文选题：重型颅脑损伤 + 开颅术　；参考：《中国处方药》2015年03期

【摘要】：目的探讨开颅术后延长硬膜下引流时间治疗重型颅脑损伤的机制和效果。方法选取收治的重型颅脑损伤开颅术后患者116例,随机分为治疗组和对照组。治疗组患者于开颅术后第4天拔除硬膜下引流管,对照组患者按常规于开颅术后第2天拔除硬膜下引流管。结果 1治疗组脑脊液中红细胞(RBC)100×106/L的时间与总蛋白(TP)量0.8 g/L的时间明显短于对照组(P0.05);2治疗组颅脑损伤后1周内平均颅内压(ICP)、ICP增高持续时间、甘露醇用量均低于对照组(P0.05);3治疗组脑积水及脑梗死发生率低于对照组(P0.05);4治疗组重残率及病死率均低于对照组,差异均具统计学意义(P0.05)。结论延长硬膜下引流时间可加速廓清患者的血性脑脊液,辅助降低颅内压,减少甘露醇用量,减少并发症发生,促进患者恢复,降低重残率及病死率,改善患者的预后。
[Abstract]:Objective to investigate the mechanism and effect of prolonged subdural drainage after craniotomy for severe craniocerebral injury. Methods 116 patients with severe craniocerebral injury after craniotomy were randomly divided into treatment group and control group. The subdural drainage tube was removed in the treatment group on the 4th day after craniotomy, and the subdural drainage tube was removed in the control group on the second day after craniotomy. Results (1) the time of 100 脳 10 6 / L RBC in CSF and 0.8 g / L of total protein TPin in the treatment group was significantly shorter than that in the control group (P 0.05). The mean ICPU ICP increased within 1 week after craniocerebral injury in the treatment group. The incidence of hydrocephalus and cerebral infarction in the treatment group was lower than that in the control group (P 0.05) and the mortality rate was lower than that in the control group (P 0.05). Conclusion prolonging the time of subdural drainage can accelerate the clearance of hemorrhagic cerebrospinal fluid, decrease intracranial pressure, reduce mannitol dosage, reduce complications, promote recovery, reduce the rate of severe disability and mortality, and improve the prognosis of patients.
【作者单位】：青岛大学医学院寒亭区人民医院;青岛大学医学院附属医院;
【分类号】：R651.15

【相似文献】