苦碟子注射液对急性脑梗死患者血清炎症因子、疗效及生活质量的影响

发布时间：2018-04-20 16:21

本文选题：苦碟子注射液 + 急性脑梗死　；参考：《中华中医药学刊》2016年04期

【摘要】：目的:观察苦碟子注射液对90例急性脑梗死患者的血清炎症因子、疗效及生活质量的影响。方法:将2012年2月—2014年11月医院神经内科收治的180例急性脑梗死患者,按照完全随机的原则均分为观察组和对照组,观察组给予常规西医治疗,观察组在此基础上给予苦碟子注射液治疗,观察苦碟子注射液对患者的血清炎症因子、疗效及生活质量的影响。结果:观察组患者的总有效率87.8%显著高于对照组64.4%,差异具有统计学意义(P0.05);两组患者治疗前,hs CRP及IL-18含量之间的差异无统计学意义(P0.05);治疗后观察组患者的hs CRP及IL-18含量显著低于对照组,差异具有统计学意义(P0.05);治疗前两组Barthel指数评分差异无统计学意义(t=3.192,P0.05),治疗后观察组(87.37±9.428)显著高于对照组(71.82±6.134),差异具有统计学意义(t=6.504,P0.05)。结论:苦碟子注射液能降低急性脑梗死患者的血清炎症因子(hs CRP、IL-18)的含量,提高临床治疗效果,显著改善患者的生活质量。
[Abstract]:Objective: To observe the effect of saucer injection on serum inflammatory factors, curative effect and quality of life in 90 patients with acute cerebral infarction. Methods: 180 patients with acute cerebral infarction treated in the Department of Neurology of hospital from February 2012 to November 2014 were divided into the observation group and the control group according to the principle of complete randomness. The observation group was treated with conventional western medicine. On this basis, the group was treated with saucer injection to observe the effect of saucer injection on serum inflammatory factors, efficacy and quality of life in the patients. Results: the total effective rate of the patients in the observation group was 87.8% significantly higher than that of the control group (64.4%), the difference was statistically significant (P0.05); the differences between the content of HS CRP and IL-18 before treatment in the two groups were different. There was no statistical significance (P0.05). The content of HS CRP and IL-18 in the observation group was significantly lower than that of the control group (P0.05). There was no statistical significance (t=3.192, P0.05) in the two groups before treatment (t=3.192, P0.05), and the observation group (87.37 + 9.428) after treatment was significantly higher than that of the control group (71.82 + 6.134), and the difference was statistically significant. (t=6.504, P0.05). Conclusion: the content of serum inflammatory factors (HS CRP, IL-18) in patients with acute cerebral infarction can be reduced by saucer injection, and the effect of clinical treatment can be improved and the quality of life of the patients can be improved significantly.

【作者单位】：宁波大学医学院附属医院;
【基金】：浙江省卫生厅科技项目(2009B134)
【分类号】：R743.3

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