医院感染对急性心肌梗死患者生存质量及体液免疫状态的影响研究

发布时间：2018-05-01 09:09

本文选题：医院感染 + 急性心肌梗死　；参考：《中华医院感染学杂志》2017年13期

【摘要】：目的研究医院感染对急性心肌梗死患者生存质量及体液免疫状态的影响,以进一步了解医院感染对急性心肌梗死患者的不良影响。方法选取2014年4月-2016年7月期间的70例急性心肌梗死并发医院感染患者为A组,70例心肌梗死无医院感染患者为B组,70名体检健康同龄者为C组,将三组研究对象的生存质量及体液免疫指标进行评估、检测及比较,并比较A组中不同感染部位患者的评估与检测结果。结果 A组的世界卫生组织生存质量测定量表简表(WHOQOL-BREF量表)心理状态、生理状态、环境领域及社会关系评分分别为(49.20±4.84)分、(41.35±4.66)分、(44.98±3.67)分及(39.88±4.20)分,均低于B组的(59.17±5.23)分、(50.21±5.32)分、(53.63±4.41)分、(51.35±5.26)分及C组的(72.53±5.73)分、(73.63±6.18)分、(68.46±4.97)分、(78.56±6.43)分,B组评分则低于C组,同时A组的体液免疫指标均低于B组及C组,B组则低于C组(P0.05),而A组中不同感染部位患者的生存质量评分及体液免疫指标则无明显差异。结论医院感染对急性心肌梗死患者生存质量及体液免疫状态的不良影响较为突出,因此认为对于急性心肌梗死患者尤其应重视医院感染的防控与诊治。
[Abstract]:Objective to study the effect of nosocomial infection on quality of life and humoral immunity in patients with acute myocardial infarction (AMI). Methods from April 2014 to July 2016, 70 patients with acute myocardial infarction complicated with nosocomial infection were selected as group A, 70 patients with myocardial infarction without nosocomial infection as group B and 70 healthy persons of the same age as group C. The quality of life (QOL) and humoral immunity (humoral immunity) of the three groups were evaluated, detected and compared, and the results of evaluation and detection of patients with different infection sites in group A were compared. Results in group A, the scores of mental state, physiological state, environmental field and social relationship were 41.35 卤4.66 and 44.98 卤3.67, respectively, and 39.88 卤4.20, respectively, in the World Health Organization quality of Life scale (WHOQOL-BREF). The scores in group B were lower than those in group B (59.17 卤5.23) and group C (53.63 卤4.41) and 73.63 卤6.18 (68.46 卤4.97) and 78.56 卤6.43 (respectively), and the scores in group B were lower than those in group C (53.63 卤4.41) and 72.53 卤5.73 (P < 0.05). At the same time, the humoral immune indexes in group A were lower than those in group B and group C were lower than those in group C (P 0.05), but there was no significant difference in quality of life (QOL) and humoral immunity in patients with different infection sites in group A. Conclusion the adverse effects of nosocomial infection on the quality of life and humoral immunity in patients with acute myocardial infarction are obvious. Therefore, the prevention, control and diagnosis and treatment of nosocomial infection should be paid more attention to in patients with acute myocardial infarction.
【作者单位】：郑州大学第一附属医院心血管内科;
【基金】：河南省高等学校重点科研基金资助项目(16A320029)
【分类号】：R542.22

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