中重度颅脑外伤睡眠障碍伴发焦虑、抑郁及疼痛的临床分析

发布时间：2018-05-03 10:33

本文选题：颅脑损伤 + 睡眠障碍　；参考：《重庆医学》2016年06期

【摘要】：目的比较中重度颅脑外伤(TBI)患者受伤1年后与健康人群睡眠障碍的发生率,观察TBI患者睡眠障碍与伴发不良症状间的关系。方法回顾性观察中重度TBI患者,通过随访方式观察TBI患者1年后的睡眠状况,及伴发焦虑、抑郁及疼痛。以健康人群作为对照,采用同样方法观察睡眠状况和伴发不良状态。睡眠障碍采用匹兹堡睡眠指数问卷(PSQI),抑郁状态使用患者健康状况问卷-9(PHQ-9),焦虑状态使用广泛性焦虑异常量表(GAD-7),疼痛评分采用类比标尺法。结果连续入选TBI患者129例。患者平均年龄38岁,入院时平均格拉斯哥昏迷评分(GCS)为9.37分,77.52%患者为男性。TBI组患者PSQI整体评分为(5.54±3.94)分,与对照组(2.67±1.71)分比较,差异有统计学意义(P0.01),44.19%的患者出现睡眠障碍(PSQI5分,总分21分)。结论睡眠障碍是中重度TBI患者受伤1年后的常见病症,经常伴发抑郁、焦虑或者疼痛。
[Abstract]:Objective to compare the incidence of sleep disorders in patients with moderate and severe craniocerebral trauma (TBI) after 1 year of injury and to observe the relationship between sleep disorders and associated adverse symptoms in patients with TBI. Methods the patients with moderate and severe TBI were observed retrospectively. The sleep status, anxiety, depression and pain in patients with TBI were observed 1 year later. The same method was used to observe sleep status and accompanying bad state of healthy people. Pittsburgh Sleep Index questionnaire (PSQI) was used for sleep disorder, PSQI for depression was used, and generalized anxiety disorder scale (GAD-7) was used for anxiety. The pain score was measured by analogue scale. Results 129 consecutive TBI patients were enrolled. The mean age of the patients was 38 years old. The mean Glasgow coma score (Glasgow coma score) at admission was 9.37 and 77.52% of the patients were male. The overall PSQI score of the patients in the TBI group was 5.54 卤3.94, which was significantly higher than that in the control group (2.67 卤1.71). The difference was statistically significant in 44.19% of the patients with sleep disorders. The total score is 21 cents. Conclusion Sleep disorder is a common disease in moderate and severe TBI patients after injury for 1 year, often accompanied by depression, anxiety or pain.
【作者单位】：天津医科大学研究生院;中国人民武装警察部队后勤学院附属医院脑系科;
【基金】：国家自然基金面上资助项目(81271392)
【分类号】：R651.15

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