高压氧联合经颅磁刺激对急性脑梗死后焦虑状态的干预效果

发布时间：2018-05-24 05:17

本文选题：脑梗死 + 焦虑状态　；参考：《宁夏医科大学》2013年硕士论文

【摘要】：目的观察高压氧（HBO）联合经颅磁刺激（TMS）对急性脑梗死后神经功能及焦虑状态的治疗效果。方法选取2011年1月-2012年12月在宁夏自治区人民医院神经内科住院的脑梗死患者134例，所用病例诊断均符合全国第四届脑血管疾病学术会议制定的诊断标准，且入院时汉密尔顿焦虑量表（HAS）评分14分。入院后，对所有病例的年龄、性别、文化程度、家庭人均收入、婚姻状况、陪护情况进行详细记录。将所收集病例分为对照组47例、HBO组44例、HBO+TMS组43例。对照组给予常规药物治疗，HBO组在常规药物治疗基础上加HBO治疗；HBO+TMS组给予常规药物、HBO及TMS治疗。采用欧洲卒中量表（ESS）、日常生活活动能力量表（ADL）、汉密尔顿焦虑量表（HAS）分别于治疗前和治疗20d后进行评定。结果⑴20d后，对照组、HBO组、HBO+TMS组焦虑的总有效率分别53.19%，77.27% 和90.70%，三组之间比较有显著性差异（X~2=16.648，P0.05）。⑵对照组、HBO组、HBO+TMS组ESS评分分别为72.15±6.62，79.02±6.99及83.09 ±6.12；ADL评分分别为27.55±4.33，22.55±3.72及19.26±3.16；HAS评分分别为16.11±4.76，14.16±3.62及12.16±4.46，三组ESS、ADL、HAS评分与治疗前比较有统计学意义（P0.05）；三组之间各项评分亦有统计学意义（P0.05）。⑶经秩和检验，婚姻状况、年龄、家庭人均收入、文化程度与焦虑严重程度有关（P0.05），而性别、陪护与焦虑程度无关（P0.05）。结论高压氧联合经颅磁刺激对急性脑梗死后焦虑状态短期内疗效确切，不仅可以改善患者焦虑状态、促进患者神经功能恢复，而且还可以提高脑梗死患者的生活质量，且未发生不良反应。
[Abstract]:Objective to observe the effect of HBO combined with transcranial magnetic stimulation (TMS) on nerve function and anxiety after acute cerebral infarction. Methods 134 patients with cerebral infarction were selected from January 2011 to December 2012 in Department of Neurology, people's Hospital of Ningxia Autonomous region. At admission, Hamilton anxiety scale (HAS14) was scored. After admission, all cases of age, sex, education, family income per capita, marital status, escort status were recorded in detail. The patients were divided into control group (n = 47) and TMS group (n = 44). The control group was treated with routine drug therapy plus HBO on the basis of routine drug therapy. The TMS group was treated with routine drugs such as HBO and TMS. The European Stroke scale (ESS), activity of Daily living (ADL) and Hamilton anxiety scale (HASS) were used to evaluate before and 20 days after treatment. Results after 120 days, the total effective rate of anxiety in the control group was 53.19% and 77.27%, respectively. There were significant differences among the three groups. The ESS scores of TMS group were 72.15 卤6.62 卤6.62 卤6.99 and 83.09, respectively. The scores of ADL in the three groups were 27.55 卤4.33 卤22.55 卤3.72 and 19.26 卤3.16 respectively, 16.11 卤4.76 卤14.16 卤3.62 and 12.16 卤4.46, respectively. The degree of education is related to the severity of anxiety. There was no correlation between the degree of anxiety and sex, but there was no relationship between the sex and the degree of anxiety. Conclusion Hyperbaric oxygen combined with transcranial magnetic stimulation is effective in the treatment of anxiety after acute cerebral infarction. It can also improve the quality of life of patients with cerebral infarction without adverse reactions.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R743.33

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