红花黄色素联合尤瑞克林治疗急性脑梗死的临床观察

发布时间：2018-06-08 14:03

本文选题：红花黄色素 + 尤瑞克林　；参考：《中国药房》2016年14期

【摘要】：目的:观察红花黄色素联合尤瑞克林治疗急性脑梗死的临床疗效及安全性。方法:将170例急性脑梗死患者,按随机数字表法分为观察组和对照组,各85例。两组患者均接受降压、调脂、控制血糖、纠正电解质紊乱、营养保护神经、降颅内压等常规治疗。对照组患者在常规治疗基础上给予红花黄色素注射液100 mg加入0.9%氯化钠注射液250 ml中,ivgtt,qd;观察组患者在对照组基础上加用尤瑞克林注射液0.15 PNA单位加入0.9%氯化钠注射液250 ml中,ivgtt,qd。两组患者均治疗2周。观察两组患者临床疗效,采用美国国立卫生研究院卒中量表(NIHSS)评分、改良RANKIN量表(MRS)评分评价神经功能缺损程度和残障程度,并比较两组患者治疗前后血常规、凝血四项、肝肾功能水平。结果:观察组患者总有效率为90.6%,显著高于对照组的63.5%,差异有统计学意义(P0.05)。治疗后,两组患者NIHSS、MRS评分均显著降低,且观察组显著低于对照组,差异有统计学意义(P0.05)。两组患者治疗前后血常规、凝血四项、肝功能、肾功能比较,差异无统计学意义(P0.05)。结论:红花黄色素联合尤瑞克林治疗急性脑梗死疗效显著,能明显改善患者的神经功能缺损程度和残障程度,且安全性较好。
[Abstract]:Objective: To observe the clinical efficacy and safety of safflower yellow and Yuri klin in the treatment of acute cerebral infarction. Methods: 170 patients with acute cerebral infarction were divided into the observation group and the control group according to the random digital table method, each of the 85 cases. The two groups were all received blood pressure lowering, lipid regulating, control blood sugar, correcting electrolyte disturbance, nourishing the nerve, reducing intracranial pressure and so on. On the basis of routine treatment, the patients in the control group were given safflower yellow injection 100 mg into 0.9% Sodium Chloride Injection 250 ml, IVGTT, QD, and the patients in the observation group were added with 0.15 PNA units of Yuri klin injection into 0.9% Sodium Chloride Injection 250 ml, IVGTT, qd. two were treated for 2 weeks. The two groups were observed. The clinical curative effect, the National Institutes of Health Stroke Scale (NIHSS) score, the improved RANKIN scale (MRS) score evaluation of the degree of neurological impairment and disability, and compared the two groups of patients before and after the treatment of blood routine, blood coagulation four, liver and kidney function level. Results: the total effective rate of patients in the observation group was 90.6%, significantly higher than the control group of 63.5%, The difference was statistically significant (P0.05). After treatment, the scores of NIHSS and MRS in the two groups were significantly lower, and the observation group was significantly lower than the control group (P0.05). The difference of blood routine, coagulation four, liver function and renal function before and after treatment in the two groups was not statistically significant (P0.05). Conclusion: Safflower Yellow combined with Yuri klin treatment. It is effective in treating acute cerebral infarction. It can significantly improve the degree of neurological impairment and the degree of disability, and is safe.
【作者单位】：湖北医药学院附属襄阳医院药学部;
【分类号】：R743.32

【相似文献】