重症监护室危重脓毒症病原菌分布及其预后分析
发布时间:2018-07-01 11:28
本文选题:严重脓毒症 + 脓毒性休克 ; 参考:《广东医学》2016年S1期
【摘要】:目的探讨重症监护室(ICU)危重脓毒症的病原菌特点及影响患者预后的危险因素,提高ICU危重脓毒症的总体救治水平。方法回顾性分析严重脓毒症、脓毒症休克患者1 088例的临床资料,如基本资料、致病菌分布及生化指标等,按患者出院时的预后分为院内死亡组与康复出院组,通过非条件logistic回归模型对相关因素进行多因素分析。结果康复出院580例(53.3%)。院内死亡组平均年龄、APACHE-Ⅱ评分、降钙素原、血乳酸水平、革兰阴性菌感染比例及耐药鲍曼不动杆菌感染比例均高于康复出院组,但院内死亡组血小板计数、血清白蛋白低于康复出院组。多因素logistic回归分析显示年龄、APACHE-Ⅱ评分、血乳酸、降钙素原及血清白蛋白是预后的独立影响因素。结论 ICU危重脓毒症在临床上有较高的发病率和病死率。年龄、APACHE-Ⅱ评分、血乳酸、降钙素原及血清白蛋白是患者预后的影响因素。
[Abstract]:Objective to investigate the pathogenic bacteria characteristics of critical sepsis in intensive care unit (ICU) and the risk factors affecting the prognosis of the patients, and to improve the overall treatment level of critical sepsis in ICU. Methods the clinical data of 1088 patients with severe sepsis and septic shock were analyzed retrospectively, such as basic data, distribution of pathogenic bacteria and biochemical indexes. The patients were divided into hospital death group and rehabilitated discharge group according to their prognosis. The related factors were analyzed by non-conditional logistic regression model. Results 580 cases (53.3%) recovered and discharged from hospital. APACHE- 鈪,
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