颅脑损伤中医证候的聚类分析研究

发布时间：2018-07-12 08:28

  本文选题：颅脑损伤 + 聚类分析　； 参考：《广西医科大学》2013年硕士论文

【摘要】：目的：采用聚类分析方法(Cluster analysis),对颅脑损伤中医证候特征及分布规律进行探讨,为建立和完善颅脑损伤的中医规范化辨证治疗体系提供科学依据。 方法：根据病例纳入标准及排除标准收集2012年5月至2013年3月广西医科大学第一附属医院中医科、神经外科病房和瑞康医院神经外科病房的颅脑损伤患者190例,记录所有患者的性别、年龄、病程、头颅CT/MRI诊断、损伤原因、合并症/并发症、主要临床表现、舌脉象等信息,运用SPSS17.0统计软件,建立所有患者的个人信息条目数据库,对证候条目采用分层聚类分析。根据聚类结果,由专家对聚类分析的初始模型讨论后,最终确定证型名称及证候特征。 结果：190例颅脑损伤患者中医证候信息横断面调查显示：面色晦暗或黧黑、皮肤青紫瘀肿、口唇紫暗或暗红、皮肤粗糙、咳痰或喉中痰鸣、大便干、淡舌、细脉等8个症状,在重型颅脑损伤与非重型颅脑损伤两组病例中,出现频率均≥30%。聚类分析结果显示：重型颅脑损伤13例急性期患者为痰瘀闭窍证,39例恢复期患者中,痰热蒙窍证20例(51.3%)、痰蒙清窍兼气血两虚证19例(48.7%)；非重型颅脑损伤70例急性期患者中,瘀热内扰证32例(45.7%)、血瘀兼气阴两伤证38例(54.3%),68例恢复期患者中,痰湿阻窍兼气虚证26例(38.2%)、瘀血阻络证21例(30.9%)、气血亏虚证21例(30.9%)。 结论：基于聚类分析研究,重型颅脑损伤急性期分为痰瘀闭窍证,恢复期分为痰热蒙窍证、痰蒙清窍兼气血两虚证；非重型颅脑损伤急性期分为瘀热内扰证、血瘀兼气阴两伤证；恢复期分为痰湿阻窍兼气虚证、瘀血阻络证及气血亏虚证。
[Abstract]:Objective: to explore the characteristics and distribution of TCM syndromes of craniocerebral injury by cluster analysis), so as to provide scientific basis for establishing and perfecting the system of TCM syndrome differentiation and treatment of craniocerebral injury. Methods: from May 2012 to March 2013, 190 patients with craniocerebral injury in Department of traditional Chinese Medicine, Department of Neurosurgery and Neurosurgical ward of Ruikang Hospital were collected according to the criteria of case inclusion and exclusion. The data of sex, age, course of disease, head CT / MRI diagnosis, injury cause, complication / complication, main clinical manifestation, tongue pulse were recorded. SPSS 17.0 statistical software was used to establish the database of personal information entries of all patients. Stratified cluster analysis was used to analyze the syndromes. According to the results of clustering, the initial model of cluster analysis was discussed by experts, and the name of syndromes and the characteristics of syndromes were finally determined. Results the cross-sectional investigation of TCM syndromes in 190 patients with craniocerebral injury showed that the symptoms were as follows: dark complexion or blackish brown skin, dark or dark red lip, rough skin, expectoration or phlegm in larynx, dry stool, light tongue, thin veins, etc. The frequency of severe craniocerebral injury and non-severe craniocerebral injury was 鈮，

本文编号：2116570