双腔起搏治疗对急性下壁心梗合并三度房室传导阻滞患者的影响

发布时间：2018-07-14 14:16

【摘要】：目的研究双腔起搏治疗对急性下壁心梗合并三度房室传导阻滞患者血清脑钠肽、心肌肌钙蛋白水平及心功能的影响。方法对比接受双腔起搏治疗的急性下壁梗死合并三度房室传导阻滞患者(观察组)、健康者(对照组)治疗前后的血清脑钠肽及心肌肌钙蛋白指标水平及观察组患者治疗前后的心功能指标水平,分析患者治疗后射血分数(LVEF)与二尖瓣舒张早期的峰值流速(E)/舒张晚期的峰值流速(A)(E/A)及Sra的相关性。结果在经过治疗后,观察组的血清脑钠肽及心肌肌钙蛋白指标水平虽然显著降低,但仍高于对照组的水平,差异均有统计学意义(P0.05)。观察组术后1个月的E/A、LVEF及Sra水平均分别显著高于术前1d的水平,术后3个月除上述指标的水平更加显著增加后,LAEF水平较术前1d亦显著增加,而LAVmin及LAVmax水平较术前1d显著降低,差异均有统计学意义(P0.05)。LVEF与Sra水平呈正相关。结论双腔起搏对急性下壁梗死合并三度房室传导阻滞的患者进行治疗,可明显改善其血清脑钠肽和心肌肌钙蛋白水平,改善心功能。
[Abstract]:Objective to study the effects of dual chamber pacing on serum brain natriuretic peptide (BNP), cardiac troponin level and cardiac function in patients with acute inferior myocardial infarction (AMI) complicated with three degree atrioventricular block (AVB). Methods the serum levels of brain natriuretic peptide and cardiac troponin in patients with acute inferior wall infarction complicated with three degree atrioventricular block (observation group) and healthy subjects (control group) before and after treatment were compared. The level of cardiac function before and after treatment, To analyze the correlation between ejection fraction (LVEF) and peak velocity of mitral valve (E) / late diastolic peak velocity (A) (E / A) and ra after treatment. Results after treatment, the levels of serum brain natriuretic peptide and cardiac troponin in the observation group were significantly decreased, but still higher than those in the control group (P0.05). In the observation group, the levels of E / Agna LVEF and Sra were significantly higher than those of 1 day after operation, and the levels of LAVmin and LAVmax decreased significantly at 3 months after operation as compared with 1 day before operation, and the level of Lef increased significantly at 3 months after operation compared with that on the 1st day before operation, and the levels of LAVmin and LAVmax were significantly lower in the observation group than in the first day before operation. The difference was statistically significant (P0.05). LVEF was positively correlated with Sra level. Conclusion Dual-chamber pacing can significantly improve the serum levels of brain natriuretic peptide and cardiac troponin and improve cardiac function in patients with acute inferior wall infarction complicated with three degree atrioventricular block.
【作者单位】：河南省三门峡市中心医院心脏重症监护室;
【分类号】：R541.7;R542.22

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