住院开放性颅脑损伤患者的患病状况调查及预后因素
发布时间:2018-07-15 11:23
【摘要】:目的探讨影响开放性颅脑损伤患者预后的相关因素。方法对该院2007年3月至2015年3月住院治疗的480例开放性颅脑损伤患者的患病状况进行回顾性分析,根据格拉斯哥预后评分(GOS)将患者分为预后不良组(1分≤GOS≤3分)和预后良好(4分≤GOS≤5分)组,采用单因素和Logistic回归分析探究开放性颅脑损伤患者颅脑清创术后预后的影响因素。结果 480例开放性颅脑损伤患者中粉碎性骨折占主要〔310例(64.58%)〕,其次为单纯性骨折170例(35.42%),且55例(11.46%)患者出现脑脊髓漏;84.17%患者合并硬膜外血肿、硬膜下血肿等其他损伤;除脑部损伤外,170例(35.42%)患者存在脑部以外部位损伤,以腹部和胸部伤为主,入院时220例(45.83%)存在颅内感染、电解质紊乱、急性肾衰竭等疾患;85.00%的患者在引流管保留条件下对创面行Ⅰ期封闭,9.79%患者因头皮大面积缺失转行Ⅰ期VSD+Ⅱ期转移皮瓣移植手术;入院时445例(92.71%)存在意识障碍,其中昏迷45例(10.11%);预后不良组的空腹血糖(FPG)水平、手术时间、心律失常、低血压、瞳孔散大、对光反射消失、颅内感染、电解质紊乱、应激性溃疡、急性肾衰竭发生率显著高于预后良好组(P0.05),而入院格拉斯哥昏迷评分(GCS)显著低于预后良好组(P0.05);多因素分析发现:FPG、入院GCS评分、心律失常、低血压、瞳孔散大、对光反射消失、颅内感染、电解质紊乱、急性肾衰竭为开放性颅脑损伤预后的危险因素(OR1,P0.05)。结论开放性颅脑损伤病情较重,常易伴发其他系统疾患,且高FPG、昏迷、心律失常、低血压、瞳孔散大、对光反射消失、颅内感染、电解质紊乱、急性肾衰竭均可影响患者预后,治疗期间需加以关注并进行干预,提高治疗预后效果。
[Abstract]:Objective to investigate the prognostic factors of patients with open craniocerebral injury. Methods from March 2007 to March 2015, 480 patients with open craniocerebral injury who were hospitalized in our hospital were retrospectively analyzed. According to Glasgow prognosis score (GOS), the patients were divided into poor prognosis group (1 鈮,
本文编号:2123898
[Abstract]:Objective to investigate the prognostic factors of patients with open craniocerebral injury. Methods from March 2007 to March 2015, 480 patients with open craniocerebral injury who were hospitalized in our hospital were retrospectively analyzed. According to Glasgow prognosis score (GOS), the patients were divided into poor prognosis group (1 鈮,
本文编号:2123898
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