高龄急性缺血性脑卒中患者认知功能障碍影响因素的Logistic回归分析
发布时间：2018-07-31 05:18
【摘要】：目的了解高龄急性缺血性脑卒中患者(acute ischemic stroke,AIS)认知功能障碍的发生率及影响因素。方法选取2013年1月~2016年9月海口市第三人民医院收治的AIS患者725例,最终纳入患者426例。根据患者病情稳定即将出院时采用简易精神状态量表(mini mental state examination,MMSE)评估其是否存在认知功能障碍,分为认知功能障碍组201例和认知功能正常组225例。应用单因素及多元Logistic回归分析急性缺血性脑卒中患者认知功能障碍的影响因素,并绘制受试者工作特征曲线来评估Logistic回归模型的效果。结果单因素及多元Logistic回归分析显示,高血压史、高脂血症、高同型半胱氨酸血症、体育锻炼、交流频率、日常生活能力是脑卒中患者发生认知功能障碍的独立影响因素(均有P0.05)。受试者工作特征曲线评价Logistic回归模型效果的曲线下面积为0.853(95%CI:0.781~0.926)。3个独立危险因素组MMSE评分低于≤3个独立危险因素组MMSE评分(t=4.183,P=0.016)。结论高龄急性缺血性脑卒中患者认知功能障碍的发生率较高,影响认知功能障碍的危险因素较多,需采取预防措施,以减少或延缓认知障碍的发生。
[Abstract]:Objective to investigate the incidence and influencing factors of cognitive impairment in elderly patients with acute ischemic stroke (acute ischemic stroke-AIS). Methods from January 2013 to September 2016, 725 patients with AIS were selected from the third people's Hospital of Haikou City, and 426 patients were included. The patients were divided into two groups: 201 patients with cognitive dysfunction and 225 patients with normal cognitive function according to the use of mini-mental state scale (mini mental state examinationmMSE) when the patient was about to be discharged from hospital. The patients were divided into two groups: 201 patients with cognitive dysfunction and 225 patients with normal cognitive function. Univariate and multivariate Logistic regression analysis was used to analyze the influencing factors of cognitive dysfunction in patients with acute ischemic stroke, and the operating characteristic curve was drawn to evaluate the effect of Logistic regression model. Results univariate and multivariate Logistic regression analysis showed that hypertension history, hyperlipidemia, hyperhomocysteinemia, physical exercise, communication frequency and daily living ability were independent influencing factors of cognitive dysfunction in stroke patients (P0.05). The area under the curve for evaluating the effect of Logistic regression model was 0.853 (95%CI:0.781~0.926). The MMSE score of three independent risk factors groups was lower than that of 鈮，
本文编号：2154539
[Abstract]:Objective to investigate the incidence and influencing factors of cognitive impairment in elderly patients with acute ischemic stroke (acute ischemic stroke-AIS). Methods from January 2013 to September 2016, 725 patients with AIS were selected from the third people's Hospital of Haikou City, and 426 patients were included. The patients were divided into two groups: 201 patients with cognitive dysfunction and 225 patients with normal cognitive function according to the use of mini-mental state scale (mini mental state examinationmMSE) when the patient was about to be discharged from hospital. The patients were divided into two groups: 201 patients with cognitive dysfunction and 225 patients with normal cognitive function. Univariate and multivariate Logistic regression analysis was used to analyze the influencing factors of cognitive dysfunction in patients with acute ischemic stroke, and the operating characteristic curve was drawn to evaluate the effect of Logistic regression model. Results univariate and multivariate Logistic regression analysis showed that hypertension history, hyperlipidemia, hyperhomocysteinemia, physical exercise, communication frequency and daily living ability were independent influencing factors of cognitive dysfunction in stroke patients (P0.05). The area under the curve for evaluating the effect of Logistic regression model was 0.853 (95%CI:0.781~0.926). The MMSE score of three independent risk factors groups was lower than that of 鈮，
本文编号：2154539
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