重症监护病房患者静脉导管相关感染病原菌及耐药性研究

发布时间：2018-08-04 10:20

【摘要】：目的研究重症监护病房(ICU)患者深静脉导管相关感染的病原菌分布及耐药性,为临床科学选用抗菌药物提供依据。方法采用回顾性调查方法,对某医院ICU住院患者中疑似静脉导管相关感染(CRBSI)者送检标本病原菌检验结果进行了统计分析。结果 102例疑似静脉导管相关感染患者中确诊CRBSI 44例,感染率为43.1%;股静脉置管患者感染率最高,占52.3%。44例CRBSI患者送检标本中共检出病原菌48株(含混合感染4例),革兰阳性球菌、革兰阴性杆菌和真菌构成比依次为54.17%、29.17%和16.67%。26株革兰阳性球菌对万古霉素、替考拉宁、利奈唑烷均敏感;革兰阴性菌仅对丁胺卡那和替加环素全部敏感。结论 CRBSI病原体以革兰阳性菌为主,且革兰阳性菌和革兰阴性菌耐药性较普遍,仅对少部分抗菌药物敏感。
[Abstract]:Objective to study the distribution and drug resistance of pathogens of deep venous catheter associated infection in (ICU) patients in intensive care unit (ICU), and to provide evidence for clinical use of antimicrobial agents. Methods A retrospective investigation was carried out to analyze the results of pathogenic bacteria in the samples of patients with suspected venous catheter-related infection (CRBSI) in a hospital with ICU. Results 44 cases (43.1%) of CRBSI were confirmed in 102 patients with suspected venous catheter-related infection, the infection rate was the highest in patients with femoral vein catheterization, accounting for 52.3.44 cases of CRBSI patients, a total of 48 strains of pathogenic bacteria (including 4 cases of mixed infection) and Gram-positive cocci were detected. The composition ratios of Gram-negative bacilli and fungi were 54.17% and 16.67.26 strains of Gram-positive cocci were sensitive to vancomycin, teicoplanin and linazolidine respectively, and Gram-negative bacteria were only sensitive to butyrona and tegicycline. Conclusion Gram-positive bacteria are the main pathogens of CRBSI, and Gram-positive bacteria and Gram-negative bacteria have common drug resistance and are only sensitive to a few antimicrobial agents.
【作者单位】：绍兴市人民医院;
【分类号】：R446.5;R459.7

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