血浆BNP对于不同类型的老年急性失代偿心力衰竭的预测价值

发布时间：2018-08-29 13:12

【摘要】：探讨血浆BNP在不同类型老年心力衰竭(简称心衰)患者中,用以预测急性失代偿心衰(ADHF)的价值。将80例心衰患者根据心脏超声结果分为左室射血分数降低的心衰(HFrEF)组25例和左室射血分数正常的心衰(HFpEF)组55例,测定初始血浆BNP值。随访1年,记录ADHF的发生并再次测定血浆BNP水平。HFpEF组年龄和BMI更高、初始BNP值更低、心绞痛病史更少、NYHAⅠ级占比更大(P0.05)。HFpEF组和HFrEF组的ADHF发生率分别为32.0%和32.7%。HFpEF患者以BNP升高122pg/ml为临界值,预测ADHF敏感度为84.8%、特异度为82.6%;HFrEF患者以BNP升高145pg/ml为临界值,预测ADHF敏感度为93.4%、特异度为47.9%。心衰患者失代偿前BNP升高,BNP升高可作为预测ADHF的指标之一。
[Abstract]:To investigate the value of plasma BNP in predicting acute decompensated heart failure (ADHF) in different types of elderly patients with heart failure. According to the results of echocardiography, 80 patients with CHF were divided into two groups: (HFrEF) group (25 cases) and (HFpEF) group (55 cases) with normal left ventricular ejection fraction (LVEF). The initial plasma BNP level was measured. After one year follow-up, the occurrence of ADHF was recorded and the plasma BNP level was determined again. The age and BMI of HFPEF group were higher, and the initial BNP value was lower. The incidence of ADHF was 32.0% in HFPEF group and 32.0% in HFrEF group. The critical value for predicting ADHF sensitivity was 84.8%, and the specificity was 82.6% for HFrEF patients, and BNP increased 145pg/ml was the critical value for 32.7%.HFpEF patients. The sensitivity and specificity of ADHF prediction were 93. 4 and 47. 9 respectively. The increase of BNP before decompensation may be used as a predictor of ADHF in patients with heart failure.
【作者单位】：武警湖北省总队医院心内科;
【分类号】：R541.6

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