冠状动脉内注射瑞替普酶对急性心肌梗死患者PCI术后的影响

发布时间：2018-09-06 08:18

【摘要】：目的观察急性心肌梗死(AMI)患者急诊经皮冠状动脉成形术(PCI)术中冠状动脉内注射瑞替普酶对患者的影响。方法 90例AMI患者随机分为治疗组和对照组,对照组直接PCI手术,治疗组在冠脉造影结束后,冠状动脉内注射瑞替普酶后行PCI。结果梗死相关动脉术后情况比较,对照组TIMI血流Ⅲ级发生率82.2%,治疗组TIMI血流Ⅲ级发生率97.8%,两者差异显著(P0.05),治疗组PCI术后24 h及1 w ST段完全回落均高于对照组(80%vs 60%;88.9%vs71.1%,P0.05),治疗组患者心肌酶和肌钙蛋白的峰值及PCI术后1 w数值均较对照组低(P0.05)。结论 AMI患者急诊PCI术中冠状动脉内注射瑞替普酶可以更进一步再通血管,减轻心肌损伤,保护心脏,安全有效。
[Abstract]:Objective to observe the effect of intracoronary injection of reteprase during emergency percutaneous transluminal coronary angioplasty (PCI) in patients with acute myocardial infarction (AMI). Methods 90 patients with AMI were randomly divided into treatment group and control group. The control group underwent direct PCI operation. The treatment group received PCI. after coronary arteriography and intracoronary injection of reteprase. Results Infarction related arteries were compared after operation. The incidence of TIMI grade 鈪，

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