CBP对重症脓毒症患者的血乳酸及血流动力学的影响

发布时间：2018-09-06 12:28

【摘要】：目的探讨连续性血液净化(CBP)对治疗重浓度症患者血乳酸水平及血流动力学的影响。方法选取我院急诊科重症监护室收治的57例重症脓毒症患者,对照组28例患者实施常规治疗,观察组29例患者实施CBP治疗。结果经治疗后,两组患者血乳酸水平变化与血流动力学指标变化显著(P0.05);随着治疗时间延长,两组患者血乳酸水平变化与血流动力学指标发生显著变化(P0.05);治疗进行72H后,两组患者较治疗前MAP、SVRI测定值均显著提高(P0.05),CI、HR测定值显著降低(P0.05),且观察组患者SVRI测定值显著高于对照组(P0.05),观察组患者28D内脏器障碍数与重症医学科治疗时间显著低于对照组(P0.05),观察组患者病死率显著低于对照组(P0.05)。结论连续性血液净化(CBP)对治疗重浓度症患者血乳酸水平有效降低,减轻患者病情严重程度,且缩短患者住院时间,但对于患者病死率控制不明显。
[Abstract]:Objective to investigate the effect of continuous blood purification (CBP) on blood lactate level and hemodynamics in patients with severe concentration syndrome. Methods 57 patients with severe sepsis, 28 patients in control group, and 29 patients in observation group were treated with CBP. Results after treatment, the changes of blood lactic acid level and hemodynamic indexes were significant in both groups (P0.05); with the prolongation of treatment time, the changes of blood lactic acid level and hemodynamic indexes in both groups were significant (P0.05); after 72H treatment, the blood lactate levels and hemodynamic indexes of the two groups were significantly changed (P0.05). The MAP,SVRI of both groups were significantly higher than that before treatment (P0.05), and the SVRI of the observation group was significantly higher than that of the control group (P0.05). The number of visceral disorders and the treatment time of the patients in the observation group were significantly lower than those in the control group (P0.05). In the control group (P0.05), the mortality of patients in the observation group was significantly lower than that in the control group (P0.05). Conclusion continuous blood purification (CBP) can effectively reduce the level of blood lactic acid in the patients with severe concentration disease, reduce the severity of the disease, and shorten the hospitalization time, but the control of mortality is not obvious.
【作者单位】：贵州省六盘水市人民医院急诊科;
【分类号】：R459.7

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