南阳地区急性ST段抬高型心肌梗死诊疗情况及10年变化趋势
发布时间：2018-09-19 16:38
【摘要】：目的:对2001-2011年南阳地区急性ST段抬高型心肌梗死(STEMI)患者的临床特征、治疗模式及院内结局进行分析,旨在评价过去10年间该地区STEMI患者诊疗情况的变化趋势。方法:随机抽取2001、2006、2011年我院急性心肌梗死住院病历,提取详细临床信息,分析其中STEMI患者临床特征、治疗模式和院内结局。结果:本研究共抽取急性心肌梗死病历234份,其中217例STEMI患者。结果显示:2001-2011年,阿司匹林、氯吡格雷及他汀的应用显著增加(阿司匹林:2001年79%,2011年94%,P0.05;氯吡格雷2001年0%,2011年95%,P0.05;他汀2001年31%,2011年95%,P0.05),β受体阻滞剂和ACEI类药物应用率仍比较低,且10年间无明显增加(β阻滞剂2001年51%,2011年55%,P0.05;ACEI类药物2001年61%,2011年59%,P0.05);未进行再灌注治疗的患者,并无显著改变(2001年43%,2011年47%;P0.05);院内病死率10年间变化差异无统计学意义(2001年9%,2011年10%;P0.05)。结论:过去10年间,南阳地区STEMI患者院内再灌注率无明显增加,病死率无显著降低,二级预防用药显著不足。医疗实践与指南之间的重要差距仍持续存在。
[Abstract]:Objective: to analyze the clinical characteristics, treatment mode and hospital outcome of patients with acute ST segment elevation myocardial infarction (STEMI) in Nanyang from 2001 to 2011, in order to evaluate the trend of diagnosis and treatment of STEMI patients in Nanyang during the past 10 years. Methods: the inpatients with acute myocardial infarction (AMI) in our hospital were randomly selected from 2001to 2006,2011, and detailed clinical information was extracted. The clinical characteristics, treatment mode and in-hospital outcome of the patients with STEMI were analyzed. Results: a total of 234 cases of acute myocardial infarction were collected, 217 of which were STEMI patients. The results showed that there was a significant increase in the use of aspirin, clopidogrel and statins between 2001 and 2011 (aspirin: 79 in 2001, 94 in 2011, P0.05; clopidogrel in 2001, 95 in 2011, P0.05; statins in 2001, 31 in 2011, 95 in 2011, P0.05), and the application rates of beta blockers and ACEI drugs were still relatively low. There was no significant increase in 尾 -blockers in 2001 (51R), 55P0.05ACEI in 2011 (61g in 2001, 595in 2011); there was no significant change in patients without reperfusion therapy (2001 43g, 2011 47g P 0.05), and there was no significant difference in the in-hospital mortality in 10 years (2001 9, 2011 10 P 0.05), and no significant change was found in the patients without reperfusion therapy (2001 43%, 2011 47% P 0.05), and there was no significant difference between them in 10 years (2001 9, 2011 10 P 0.05). Conclusion: in the past 10 years, the in-hospital reperfusion rate of STEMI patients in Nanyang area was not significantly increased, the mortality rate was not significantly decreased, and the secondary prophylaxis medication was significantly inadequate. Important gaps between medical practice and guidelines persist.
【作者单位】： 郑州大学附属南阳医院南阳市中心医院心内科;
【基金】：卫生公益性行业科研专项(No:201202025) 国家科技支撑计划项目(No:2013BAI09B00)
【分类号】：R542.22
本文编号：2250710
[Abstract]:Objective: to analyze the clinical characteristics, treatment mode and hospital outcome of patients with acute ST segment elevation myocardial infarction (STEMI) in Nanyang from 2001 to 2011, in order to evaluate the trend of diagnosis and treatment of STEMI patients in Nanyang during the past 10 years. Methods: the inpatients with acute myocardial infarction (AMI) in our hospital were randomly selected from 2001to 2006,2011, and detailed clinical information was extracted. The clinical characteristics, treatment mode and in-hospital outcome of the patients with STEMI were analyzed. Results: a total of 234 cases of acute myocardial infarction were collected, 217 of which were STEMI patients. The results showed that there was a significant increase in the use of aspirin, clopidogrel and statins between 2001 and 2011 (aspirin: 79 in 2001, 94 in 2011, P0.05; clopidogrel in 2001, 95 in 2011, P0.05; statins in 2001, 31 in 2011, 95 in 2011, P0.05), and the application rates of beta blockers and ACEI drugs were still relatively low. There was no significant increase in 尾 -blockers in 2001 (51R), 55P0.05ACEI in 2011 (61g in 2001, 595in 2011); there was no significant change in patients without reperfusion therapy (2001 43g, 2011 47g P 0.05), and there was no significant difference in the in-hospital mortality in 10 years (2001 9, 2011 10 P 0.05), and no significant change was found in the patients without reperfusion therapy (2001 43%, 2011 47% P 0.05), and there was no significant difference between them in 10 years (2001 9, 2011 10 P 0.05). Conclusion: in the past 10 years, the in-hospital reperfusion rate of STEMI patients in Nanyang area was not significantly increased, the mortality rate was not significantly decreased, and the secondary prophylaxis medication was significantly inadequate. Important gaps between medical practice and guidelines persist.
【作者单位】： 郑州大学附属南阳医院南阳市中心医院心内科;
【基金】：卫生公益性行业科研专项(No:201202025) 国家科技支撑计划项目(No:2013BAI09B00)
【分类号】：R542.22
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