新活素对急性ST段抬高型心肌梗死患者急诊PCI术后心功能及短期预后的影响

发布时间：2018-11-18 06:22

【摘要】：目的观察新活素对于急诊经皮冠状动脉成形术(PCI)术后急性ST段抬高型心肌梗死(STEMI)患者心功能及短期预后的影响。方法入选70例急诊PCI术后的STEMI患者,随机分为对照组36例和新活素组34例,对照组给予常规西医治疗,新活素组在常规西医治疗的基础上联合使用新活素注射液。观察术后3个月两组之间在心动能及短期预后方面的差异。结果新活素组与对照组在基线资料和临床特征方面无差异(P0.05),3个月后随访发现新活素组左心室射血分数(LVEF)明显高于对照组(55.7±5.1 vs.48.3±8.4,P0.01),左心室舒张末期内径值明显小于对照组(52.3±3.1 vs.56.1±2.8,P0.01),同时在心指数方面也比对照组有明显提升(3.5±0.9 vs.3.0±0.6,P0.05)。另外,新活素组患者心功能恶化发生率显著减少(8.82%vs.27.8%,P0.05)。结论新活素可显著提升急诊PCI术后STEMI患者的心功能,改善心室重构及短期预后。
[Abstract]:Objective to investigate the effects of neovasin on cardiac function and short-term prognosis in patients with acute ST segment elevation myocardial infarction (STEMI) after (PCI). Methods 70 patients with STEMI after PCI were randomly divided into control group (n = 36) and neovasin group (n = 34). The control group was treated with routine western medicine, and the new livingin group was treated with Xinhuoxin injection on the basis of routine western medicine treatment. To observe the difference of cardiac function and short-term prognosis between the two groups 3 months after operation. Results there was no significant difference in baseline data and clinical features between the neovasin group and the control group (P0.05). After 3 months of follow-up, the left ventricular ejection fraction (LVEF) in the neovasin group was significantly higher than that in the control group (55.7 卤5.1 vs.48.3 卤8.4). The left ventricular end-diastolic diameter was significantly lower than that of the control group (52.3 卤3.1 vs.56.1 卤2.8 vs.56.1 P0.01), and the cardiac index was significantly higher than that of the control group (3.5 卤0.9 vs.3.0 卤0.6). P0.05). In addition, the incidence of cardiac function deterioration was significantly decreased in neovasin group (8.82 vs 27.8P, P 0.05). Conclusion Neoactin can significantly improve cardiac function, ventricular remodeling and short-term prognosis in patients with STEMI after emergency PCI.
【作者单位】：上海市普陀区中心医院心内科;
【基金】：上海市医学重点专科建设项目资助(编号:ZK2015A17)
【分类号】：R542.22

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