参麦注射液对老年急性脓毒血症患者血清C反应蛋白、降钙素原、肿瘤坏死因子-α水平的影响
发布时间：2019-01-27 17:12
【摘要】：目的探讨参麦注射液对老年急性脓毒血症患者血清C反应蛋白(CRP)、降钙素原(PCT)、肿瘤坏死因子(TNF)-α水平的影响。方法选取老年急性脓毒血症患者96例,随机分为两组,各48例。对照组采用常规治疗,观察组在对照组基础上采用参麦注射液治疗,采用双抗体夹心酶联免疫吸附(DAS-ELISA)检测血清CRP、PCT、TNF-α水平,参照序贯器官衰竭评分(SOFA)与急性生理学与慢性健康状况评分(APACHE)Ⅱ标准评定预后状况。结果观察组治疗有效率明显高于对照组(P0.05)。治疗后,两组血清指标(CRP、PCT、TNF-α)与预后状况(SOFA、APACHEⅡ)均明显低于治疗前,观察组上述指标均明显低于对照组(P0.05),两组患者均未出现任何药物不良反应。结论参麦注射液有助于显著降低老年急性脓毒血症患者血清CRP、PCT、TNF-α等炎症介质水平,改善临床疗效与预后。
[Abstract]:Objective to investigate the effect of Shenmai injection on serum C-reactive protein (CRP),) calcitonin procalcitonin (PCT),) tumor necrosis factor (TNF)-伪) levels in elderly patients with acute sepsis. Methods 96 aged patients with acute sepsis were randomly divided into two groups, 48 cases each. The control group was treated with routine therapy, the observation group was treated with Shenmai injection on the basis of the control group, and the serum CRP,PCT,TNF- 伪 level was detected by double antibody sandwich enzyme linked immunosorbent assay (DAS-ELISA). Prognostic status was evaluated by (SOFA) and (APACHE) 鈪，
本文编号：2416497
[Abstract]:Objective to investigate the effect of Shenmai injection on serum C-reactive protein (CRP),) calcitonin procalcitonin (PCT),) tumor necrosis factor (TNF)-伪) levels in elderly patients with acute sepsis. Methods 96 aged patients with acute sepsis were randomly divided into two groups, 48 cases each. The control group was treated with routine therapy, the observation group was treated with Shenmai injection on the basis of the control group, and the serum CRP,PCT,TNF- 伪 level was detected by double antibody sandwich enzyme linked immunosorbent assay (DAS-ELISA). Prognostic status was evaluated by (SOFA) and (APACHE) 鈪，
本文编号：2416497
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