腹腔镜术后腹腔灌洗、持续循环式腹膜透析治疗重症急性胰腺炎的临床研究
发布时间：2019-03-01 16:43
【摘要】：目的观察腹腔镜术后腹腔灌洗、持续循环式腹膜透析(CCPD)治疗重症急性胰腺炎(SAP)的临床效果及安全性。方法将68例SAP患者随机分为治疗组32例与对照组36例,治疗组于腹腔镜下手术,术后灌洗引流与CCPD交替进行,病情稳定后(约需3 d)单一行腹腔灌洗;对照组给予常规治疗。结果治疗组急性生理与慢性健康评分(APACHEⅡ)及Balthazar CT积分从第1天即下降明显(P0.05),而对照组在第3天才显著下降,且治疗组各时点积分均较对照组明显降低(P0.05)。治疗组各时相点血浆中促炎细胞因子肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)及C反应蛋白(CRP)含量与治疗前比较呈明显降低趋势(P0.01),白细胞介素-10(IL-10)含量呈明显升高趋势(P0.01),与对照组比较各时点各细胞因子含量差异有统计学意义意义(P0.05)。结论腹腔镜术后灌洗引流与CCPD治疗SAP具有方法简单、安全、快捷、创伤小、并发症少及无需抗凝等优点,无血液动力学影响,患者有较好的耐受性等特点,是一种治疗SAP的有效方法。
[Abstract]:Objective to observe the efficacy and safety of peritoneal lavage and continuous circulation peritoneal dialysis (CCPD) in the treatment of severe acute pancreatitis (SAP) after laparoscopic surgery. Methods 68 patients with SAP were randomly divided into treatment group (n = 32) and control group (n = 36). The patients in the treatment group were operated under laparoscopy, the drainage was alternately performed with CCPD after operation, and the patients in the control group were given routine treatment after stable condition (about 3 days). Results the acute physiological and chronic health scores (APACHE 鈪，
本文编号：2432611
[Abstract]:Objective to observe the efficacy and safety of peritoneal lavage and continuous circulation peritoneal dialysis (CCPD) in the treatment of severe acute pancreatitis (SAP) after laparoscopic surgery. Methods 68 patients with SAP were randomly divided into treatment group (n = 32) and control group (n = 36). The patients in the treatment group were operated under laparoscopy, the drainage was alternately performed with CCPD after operation, and the patients in the control group were given routine treatment after stable condition (about 3 days). Results the acute physiological and chronic health scores (APACHE 鈪，
本文编号：2432611
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