血糖水平对重组组织型纤维蛋白酶原激活剂静脉溶栓治疗急性缺血性脑卒中预后的影响
发布时间:2019-05-09 23:06
【摘要】:目的探讨血糖水平对重组组织型纤维蛋白酶原激活剂(rt-PA)静脉溶栓治疗急性缺血性脑卒中预后的影响。方法选择2014年5月至2015年7月在该院接受静脉rt-PA溶栓治疗的118例急性缺血性脑卒中患者。根据溶栓前血糖水平分为血糖正常组(血糖7.8 mmol/L,n=49),血糖偏高组(7.8~11.1 mmol/L,n=42),高血糖组(血糖11.1 mmol/L,n=27)。采用Rankin量表(mRS)评价神经功能恢复情况,根据mRS评分分为预后良好组(n=71)和预后不良组(n=47)。分析影响rt-PA静脉溶栓治疗急性缺血性脑卒中预后的因素,比较不同血糖水平患者的预后。结果(1)多因素Logistic回归分析显示,影响rt-PA预后的危险因素有:溶栓前血糖、溶栓前美国国立卫生研究院卒中量表(NIHSS)评分、伴有糖尿病、溶栓后2 h及24 h收缩压。(2)血糖偏高组和高血糖组颅内出血发生率、症状性颅内出血发生率、病死率、预后不良发生率明显高于血糖正常组(P0.05)。结论溶栓前血糖≥7.8 mmol/L的急性缺血性脑卒中患者rt-PA静脉溶栓治疗预后较差,血糖水平是影响静脉rt-PA溶栓治疗预后的独立因素。
[Abstract]:Objective to investigate the effect of blood glucose level on the prognosis of acute ischemic stroke treated with recombinant tissue protease activating agent (rt-PA). Methods from May 2014 to July 2015, 118 patients with acute ischemic stroke were treated with intravenous rt-PA thrombolysis. According to the level of blood glucose before thrombolysis, they were divided into normal blood glucose group (7.8 mmol/L,n=49), hyperglycemia group (7.8 鈮,
本文编号:2473159
[Abstract]:Objective to investigate the effect of blood glucose level on the prognosis of acute ischemic stroke treated with recombinant tissue protease activating agent (rt-PA). Methods from May 2014 to July 2015, 118 patients with acute ischemic stroke were treated with intravenous rt-PA thrombolysis. According to the level of blood glucose before thrombolysis, they were divided into normal blood glucose group (7.8 mmol/L,n=49), hyperglycemia group (7.8 鈮,
本文编号:2473159
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