上海地区不同科室医师治疗阿尔茨海默病患者选用抗精神病药物的调查

发布时间：2018-01-04 18:27

本文关键词：上海地区不同科室医师治疗阿尔茨海默病患者选用抗精神病药物的调查　出处：《中国老年学杂志》2016年08期 　论文类型：期刊论文

【摘要】：目的了解上海地区不同科室医师治疗阿尔茨海默病(AD)时选用抗精神病药物情况。方法采用自制调查表,对上海地区有老年痴呆或认知障碍门诊的临床医师进行调查。结果精神科、内科、神经内科医师在年龄、性别、学历、每月诊断AD例数及诊断轻中重AD比例上,差异无统计学意义(P0.05);精神科、内科、神经内科医师在职称、医院等级、合并抗精神病药物比例上,差异有统计学意义(P0.01);首选抗精神病药物中,92.6%的精神科医师、96.6%的内科医师、91.5%的神经内科医师在首选的非典型抗精神病药物(包括奥氮平、利培酮、喹硫平、阿立哌唑、氯氮平)上,三科室之间的差异无统计学意义(P0.05);在利培酮、喹硫平、奋乃静、奥氮平、氯氮平等药物的选用上,三科室之间的差异无统计学意义(P0.05)。结论上海地区医师治疗AD患者时,合并处方抗精神病药物较为普遍。精神科、内科、神经内科医师在首选药物中选用非典型抗精神病药物种类无显著差异。
[Abstract]:Objective to investigate the use of antipsychotics in the treatment of Alzheimer's disease (AD) by doctors in different departments in Shanghai. Methods Self-made questionnaire was used. The clinical doctors with senile dementia or cognitive impairment in Shanghai were investigated. Results the age, sex and educational background of psychiatrists, internal medicine and neurologists were investigated. There was no significant difference in the number of AD cases diagnosed each month and the proportion of mild, moderate and severe AD diagnosis (P 0.05). There were significant differences in the proportion of professional title, hospital grade and combined antipsychotic drugs among psychiatrists, internal medicine and neurologists (P 0.01). 91.5% of neurologists were selected as atypical antipsychotics (including olanzapine and risperidone). There was no significant difference between the three departments (P 0.05) on quetiapine, aripiprazole and clozapine. In the selection of risperidone, quetiapine, perphenazine, olanzapine and clozapine, there was no significant difference among the three departments. The combination prescription antipsychotics is more common. There is no significant difference in the choice of atypical antipsychotics among psychiatrists, internal medicine and neurologists.
【作者单位】：上海嘉定区精神卫生中心;上海交通大学医学院附属精神卫生中心;浙江省人民医院;
【基金】：国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873) 上海市科委医学引导项目(15411961400)
【分类号】：R749.3
【正文快照】： 阿尔茨海默病(AD)已经成为我国社会和医学界面临的严峻问题,日益受到政府和医学工作者的重视〔1〕。历来人们都把重点放在痴呆患者认知症状的研究及治疗上,近年来才逐渐认识到非认知的精神行为症状对患者本人、家人和社会的巨大影响〔2〕。1996年国际老年精神病学会(IPA),把“

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