精神分裂症患者1年中不同治疗阶段工作状况的预测因素分析

发布时间：2018-01-28 23:13

本文关键词： 精神分裂症工作状况分类回归树　出处：《广东医学》2017年19期 　论文类型：期刊论文

【摘要】：目的对精神分裂症患者在不同治疗阶段的工作状况建立预测和分类模型,以探讨其工作状况的预测因素。方法收集随机分到综合治疗组和常规药物治疗组的170例精神分裂症患者在基线及3、6、12个月的工作状况和人口学、社会和临床指标,用分类回归树的方法建立预测模型。结果基线时首次发病年龄预测患者是否工作的分割点是25岁,模型正确估计了患者总数的67.6%;随访3个月时,自知力水平总分大于13分、接受综合治疗和受教育年限大于9年可以产生82.6%的节点(工作的患者),模型正确估计了患者总数的73.4%;随访6个月和12个月时,个人和社会功能大于70或72分。病程或受教育年限是预测工作状况的主要指标,模型总体预测准确率分别为74.8%和73.7%。结论急性期的患者其工作状况主要和首次发病年龄、精神症状严重程度有关;恢复期患者工作状况主要和自知力的水平、是否接受综合治疗有关;巩固期患者工作状况主要和社会功能的恢复情况、病程以及受教育程度有关。
[Abstract]:Objective to establish a prediction and classification model for the work status of schizophrenic patients in different stages of treatment. Methods 170 schizophrenic patients who were randomly assigned to the comprehensive treatment group and the routine drug treatment group were collected at baseline and in 3 months and 12 months of work status and demography. Social and clinical indicators, using the method of classification and regression tree to establish a prediction model. Results the first onset of age at baseline to predict whether the patient work division point is 25 years old, the model correctly estimated the total number of patients 67.6%; At 3 months follow-up, the total score of insight level was more than 13 points, and the number of nodes (working patients) could be 82.6% after comprehensive treatment and education for more than 9 years. The model correctly estimated 73.4% of the total number of patients. At 6 and 12 months follow-up, the individual and social function were more than 70 or 72 points. Course of disease or length of education were the main predictors of work status. The overall predictive accuracy of the model was 74.8% and 73.7 respectively. Conclusion the work status of the patients in the acute stage is mainly related to the age of the first onset and the severity of mental symptoms. The working condition of convalescent patients is mainly related to the level of insight and whether or not they accept comprehensive treatment. The work status of patients in consolidation period is mainly related to the recovery of social function, the course of disease and the level of education.
【作者单位】：广州市惠爱医院、广州医科大学附属脑科医院成人精神科;北京师范大学心理学部;
【基金】：国家自然科学基金资助项目(编号:81671334) 广州市科技计划项目(编号:2014Y2-00105)
【分类号】：R749.3
【正文快照】： 职业状况是精神分裂症患者面临的一个重要问题[1]。职业康复是精神分裂症患者康复治疗的最终目标之一,能够帮助患者避免较低的生活质量、提升自尊和促进长期治疗的疗效[1-2]。以往的研究发现既往的工作经验、教育水平、临床特征包括病程、症状的严重程度、首次发病年龄等都是

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