米氮平结合帕潘立酮治疗高血压合并抑郁焦虑症的效果

发布时间：2018-02-24 19:12

本文关键词： 米氮平帕潘立酮高血压抑郁症　出处：《广东医学》2014年20期 　论文类型：期刊论文

【摘要】：目的观察米氮平结合帕潘立酮治疗高血压合并抑郁焦虑症的临床效果。方法选择接受治疗的高血压合并抑郁焦虑症患者90例,分为观察组和对照组各45例,对照组给予常规降血压药物配合心理疏导进行治疗,观察组在常规治疗的基础上加用米氮平联合帕潘立酮进行治疗,4周为一疗程,1个疗程后,通过对比两组患者焦虑抑郁程度和血压改善状况进行评价。结果观察组患者降压疗效总有效率为91.11%(41/45),明显高于对照组的73.33%(33/45),观察组抗抑郁疗效总有效率为93.56%(41/45),明显高于对照组的85.65%(34/45),差异均有统计学意义(P0.05)。观察组2例(4.4%)患者出现嗜睡,1例(2.2%)出现头痛、恶心,2例(4.4%)出现体重增加,随着治疗继续,逐渐恢复正常。结论米氮平结合帕潘立酮治疗高血压合并抑郁焦虑症能够有效降低患者的焦虑程度,改善患者血压状态,建议在临床上推广应用。
[Abstract]:Objective to observe the clinical effect of metozapine combined with Papanlitone in the treatment of hypertension with depression and anxiety. Methods 90 patients with hypertension and depression anxiety were selected and divided into two groups: observation group (n = 45) and control group (n = 45). The control group was treated with conventional antihypertensive drugs combined with psychological dredging. The observation group was treated with miazapine combined with Papanlitone for a course of 4 weeks, one course of treatment, one course of treatment on the basis of routine treatment. Results the total effective rate of lowering blood pressure in the observation group was 91.1141 / 45, which was significantly higher than that in the control group (73.33 / 33 / 45). The total effective rate of antidepressant effect in the observation group was 93.56 / 41 / 45, which was significantly higher than that in the control group. In the control group, there was a significant difference between 34 / 45 and 85.65% (P < 0.05). In the observation group, 2 cases (4. 4%) developed drowsiness and 1 case (2. 22%) developed headache. (4. 4) weight gain occurred in 2 patients with nausea, and gradually returned to normal as treatment continued. Conclusion Mianzapine combined with Papanlitone can effectively reduce anxiety and improve blood pressure in patients with hypertension and depression anxiety. It is suggested that it be popularized in clinic.
【作者单位】：江苏省无锡市第二人民医院神经内科;
【分类号】：R544.1;R749

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