糖尿病视网膜病变合并抑郁状态患者的临床评价

发布时间：2018-03-09 18:37

  本文选题：糖尿病视网膜病变　切入点：抑郁状态　出处：《中国糖尿病杂志》2014年03期 　论文类型：期刊论文

【摘要】：目的评价DR合并抑郁状态患者的生命质量和人格特征,探讨其炎症因子变化。方法选取新诊断DR(背景期)患者164例,按照抑郁自评量表(SDS)评分分为抑郁状态(DRD)组114例和非抑郁状态(N-DRD)组50例,采用艾森克人格量表和糖尿病生命质量量表评价,检测生化指标和炎症因子。结果 DR合并抑郁状态患病率69.51%。与N-DRD组相比,DRD组满意程度[(36.70±8.38)vs(29.92±8.15)分]、影响程度[(47.51±11.29)vs(39.60±10.37)分]、忧虑程度Ⅰ[(13.56±7.37)vs(8.28±2.39)分]、忧虑程度Ⅱ[(9.23±4.24)vs(5.80±2.22)分]、神经质[(4.56±3.33)vs(1.84±0.06)分]得分高,内外向[(7.98±3.15)vs(9.60±2.65)分]得分低;病程、SBP、FPG、HbA1c、TG、高敏C反应蛋白(hsC-RP)、IL-6、TNF-α、皮质醇和胰岛素抵抗指数(HOMA-IR)水平均增高(P均0.05)。SDS评分与hsC-RP、TNF-α呈正相关。结论 DR易合并抑郁状态,且神经质、内向性格、生命质量低者更易导致抑郁状态,hsC-RP和TNF-α是抑郁状态的独立影响因素。
[Abstract]:Objective to evaluate the quality of life (QOL) and personality characteristics in patients with Dr complicated with depression and to explore the changes of inflammatory factors. Methods 164 newly diagnosed patients with DRs (background period) were selected. According to the self-rating depression scale (SDS) score, the patients were divided into two groups: the depression group (n = 114) and the non-depression group (n = 50). Eysenck personality scale and diabetes quality of life scale were used to evaluate the quality of life. Results compared with N-DRD group, the degree of satisfaction [36.70 卤8.38 vs 29.92 卤8.15], the degree of influence [47.51 卤11.29 vs 39.60 卤10.37], the anxiety degree 鈪，

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