抑郁症静息态EEG前后部脑电活动

发布时间：2018-05-26 00:11

本文选题：抑郁症 + 静息态EEG　；参考：《智能系统学报》2014年02期

【摘要】：抑郁症病人静息态EEG存在左右脑半球神经电活动强度不对称的现象。分析了抑郁症的大脑前后部脑电信号不对称性的变化,并在正常组、抑郁症未用药组和抑郁症用药组三组被试中进行了分析。分析过程首先将静息态EEG进行快速傅里叶变换(FFT),将时域的EEG信号转换为频域的相关信息。将频域划分频带,导出各个频带各个通道的电压密度后,用电压密度值计算比较脑前后部神经电活动的相对强弱。结果发现正常人脑前部神经电活动强于脑后部,抑郁症未用药病人脑前部神经电活动弱于脑后部。用药的抑郁症病人脑前后部神经电活动的相对强弱有所改善。该结论有助于基于生物标记的抑郁症自动诊断和和治疗效果预测。
[Abstract]:In patients with depression, the intensity of neuroelectric activity in left and right hemispheres is asymmetrical in resting EEG. The asymmetry changes of EEG in the anterior and posterior part of the brain were analyzed in the normal group, the untreated group and the depressive medication group. In the process of analysis, the EEG in the rest state is firstly transformed into the FFTT, and the EEG signal in the time domain is converted into the relevant information in the frequency domain. After the frequency domain is divided into frequency bands and the voltage density of each channel is derived, the relative strength of the neuroelectric activity in the anterior and posterior part of the brain is calculated and compared with the voltage density value. The results showed that the anterior part of the normal human brain was stronger than the posterior part of the brain, and the anterior part of the depressive patients was weaker than the posterior part of the brain. The relative strength of neuroelectric activity in the anterior and posterior part of the brain was improved in depressive patients treated with drugs. This conclusion is helpful to automatic diagnosis and treatment prediction of depression based on biomarkers.
【作者单位】：北京工业大学国际WIC研究院磁共振成像脑信息学北京市重点实验室;首都医科大学附属北京安定医院;
【基金】：国家国际科技合作专项资助项目(2013DFA32180) 国家自然科学基金资助项目(61272345) 中国科学院、国家外国专家局创新团队国际合作伙伴计划资助项目
【分类号】：R749.4;R741.044

【共引文献】