强迫症模糊情境下决策能力的事件相关电位研究

发布时间：2018-05-28 17:40

本文选题：强迫症 + 决策　；参考：《中国临床心理学杂志》2017年06期

【摘要】：目的:探讨强迫症在模糊情境下的决策能力及自我监控能力。方法:28例强迫症患者接受爱荷华博弈测验(the revised Iowa Gambling Task,IGT),同时利用Neuroscan 64导脑电仪追踪记录其事件相关电位,并与28例正常对照者作比较。结果:(1)IGT总净得分对照组高于强迫症组,组别效应显著(F=4.15,P=0.047);强迫症组在block4上的净得分显著低于对照组(t=-2.03,P=0.048),block5(P=0.067)和block6(P=0.052)上得分低于对照组,但未达到统计学差异;(2)强迫症组FRN原始波(F=4.782,P=0.033)和差异波(输-赢)(F=4.022,P=0.05)波幅均低于对照组,反馈相关脑区活动异常。结论:模糊情境下,强迫症的决策能力及自我监控能力受损;负性反馈后,其自上而下的自我调整能力降低。
[Abstract]:Objective: to explore the ability of decision-making and self-monitoring of obsessive-compulsive disorder (OCD) in fuzzy context. Methods Twenty eight patients with obsessive-compulsive disorder received the revised Iowa Gambling TaskIGT test, and their event-related potentials were recorded by Neuroscan 64 electroencephalograph and compared with 28 normal controls. Results the total net score of block4 in the control group was significantly higher than that in the obsessive-compulsive disorder group, and the net score on block4 in the obsessive-compulsive disorder group was significantly lower than that in the control group, and in the obsessive-compulsive disorder group was lower than that in the control group. But the amplitudes of FRN original wave FN 4.782 P0. 033) and differential wave (F0. 022% P0. 05) in obsessive-compulsive disorder group were lower than those in control group, and the activity of brain regions related to feedback was abnormal in obsessive-compulsive disorder group. Conclusion: obsessive-compulsive disorder (OCD) has impaired ability of decision making and self-monitoring under fuzzy situation, and its ability of self-adjustment from top to bottom is decreased after negative feedback.
【作者单位】：安徽医科大学医学心理学系;安徽医科大学第一附属医院神经内科;安徽省精神卫生中心;
【基金】：安徽医科大学博士科研资助项目(编号:XJ201533) 安徽省高校人文社会科学重点研究基地安徽医科大学医学人文研究中心招标项目(SK2016A0489)
【分类号】：R749.7

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