额颞叶变性的异质性
发布时间：2018-09-09 18:12
【摘要】：额颞叶变性(frontotemporal lobar degeneration,FTLD)是一组常见的痴呆症候群,尤其是在小于65岁的患者中。它包括一组以进行性行为异常、执行功能障碍或语言损害为主要特征的神经退行性疾病。因其潜在基因和病理的多样性,FTLD表现为多种临床表型,且其临床和神经影像表现呈现不同程度的重叠。额颞叶变性临床、基因、病理的异质性为早期正确诊断、精准治疗疾病提出了极大挑战。
[Abstract]:Frontotemporal lobe degeneration (frontotemporal lobar degeneration,FTLD) is a common group of dementia, especially in patients under 65 years of age. It consists of a group of neurodegenerative diseases characterized by progressive behavioral abnormalities, executive dysfunction or language impairment. Because of the diversity of its potential gene and pathology, FTLD presents a variety of clinical phenotypes, and its clinical and neuroimaging manifestations show different degrees of overlap. The clinical, genetic and pathological heterogeneity of frontotemporal lobe degeneration presents a great challenge for early correct diagnosis and accurate treatment of diseases.
【作者单位】： 中国人民解放军总医院南楼神经内科;
【分类号】：R749.1
本文编号：2233175
[Abstract]:Frontotemporal lobe degeneration (frontotemporal lobar degeneration,FTLD) is a common group of dementia, especially in patients under 65 years of age. It consists of a group of neurodegenerative diseases characterized by progressive behavioral abnormalities, executive dysfunction or language impairment. Because of the diversity of its potential gene and pathology, FTLD presents a variety of clinical phenotypes, and its clinical and neuroimaging manifestations show different degrees of overlap. The clinical, genetic and pathological heterogeneity of frontotemporal lobe degeneration presents a great challenge for early correct diagnosis and accurate treatment of diseases.
【作者单位】： 中国人民解放军总医院南楼神经内科;
【分类号】：R749.1
【相似文献】
相关期刊论文 前5条
1 周玉颖;李攀;;额颞叶变性临床诊断标准研究进展[J];中国神经免疫学和神经病学杂志;2014年05期
2 冉红;陈玉霞;盛婧;王婷婷;;额颞叶挫裂伤后精神障碍的临床观察及护理[J];实用医药杂志;2008年11期
3 吴建新;陈先文;;额颞叶变性的研究进展[J];第二军医大学学报;2007年02期
4 王丽玲;王刚;陈生弟;;额颞叶变性的临床表现、分型及神经病理学的研究进展[J];诊断学理论与实践;2010年04期
5 ;[J];;年期
，本文编号：2233175
本文链接：https://www.wllwen.com/yixuelunwen/jsb/2233175.html
最近更新
教材专著
